Study of Ocular Risk Factors for Primary Open-Angle Glaucoma

Garg, Pragati; Jha, Monalisa; Singh, Luxmi; Kawatra, Ishani; Lal, Bishan Bihari

doi:10.18410/jebmh/2016/244

Cited by 6 publications

(10 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, 81 (36%) participants had HTN. This was comparable with a study done by Garg et al 21 where HTN was seen in 35.1% of their participants.…”

Section: Discussionsupporting

confidence: 91%

Severity of primary open-angle glaucoma in patients with hypertension and diabetes

Khatri¹,

Shrestha²,

Thapa³

et al. 2018

DMSO

View full text Add to dashboard Cite

BackgroundPrimary open-angle glaucoma (POAG) is a progressive optic neuropathy with numerous risk factors. Its severity with associated risk factors remains a widely debated topic.AimTo evaluate the severity of POAG in patients with hypertension (HTN) and diabetes or both.Patients and methodsThis hospital-based, cross-sectional descriptive study was conducted for a period of 18 months from January 2016 to June 2017. Diagnosed cases of POAG were evaluated for severity with associated risk factors.ResultsA total of 221 patients were enrolled in the study. The mean age of the patients was 54.4 (SD ± 15.9) years with a male to female ratio of 0.93:1. Of the 221 patients, 68 (31%) had a family history of POAG. Mean intraocular pressure was 15.8±4.87 mmHg, and mean central corneal thickness was 535.4±34.9 μm. A total of 81 (36%) patients had HTN, 21 (9.50%) had diabetes mellitus (DM), and 15 (6.80%) had both HTN and DM. Analysis using SPSS version 20 was done. The severity of POAG was found to be significantly higher in patients with HTN, DM, or both when evaluated on the basis of anatomical and functional loss.ConclusionPOAG patients with HTN, DM, or both were found to have more severe POAG. Patients with these risk factors could represent “high-risk patients” with POAG. Patients with HTN and DM, or both may require evaluations on a more frequent basis to access the progression/severity of POAG.

show abstract

“…In this study, 81 (36%) participants had HTN. This was comparable with a study done by Garg et al 21 where HTN was seen in 35.1% of their participants.…”

Section: Discussionsupporting

confidence: 91%

Severity of primary open-angle glaucoma in patients with hypertension and diabetes

Khatri¹,

Shrestha²,

Thapa³

et al. 2018

DMSO

View full text Add to dashboard Cite

show abstract

“…Diabetes cause microvascular damage and may affect vascular auto regulation of retina and optic nerve. 2 This maybe an added factor in our study, which showed higher incidence of glaucoma (12.4%) compared to general population. It maybe because the study was done in diabetic patients.…”

Section: Resultsmentioning

confidence: 56%

“…Among the 750 patients, 93 (12.4%) had glaucoma, which is high compared to other studies done in general population 2,6 (Table 4) (Figure 4). In our study, glaucoma was significantly more in diabetic patients with HT53 (15.2%) than patients without HT40 (10.0%) p value significant at 0.05 level (Table 5) ( Figure 5).…”

Section: Resultsmentioning

confidence: 58%

“…Primary open-angle glaucoma is more prevalent in those with lower perfusion pressures. 2,8 Higher ocular perfusion pressure offers relative protection from glaucomatous damage in young patients, but is a risk factor in older patients. 3,9 Patients at both extremes of blood pressure spectrum show an increased prevalence of glaucoma.…”

Section: Resultsmentioning

confidence: 99%

“…1 Worldwide, the reported prevalence for primary open-angle glaucoma varies between 1.62% and 3.51%. 2 Several studies suggest that both HT and hypotension are associated with increased risk of primary open-angle glaucoma. Elevated blood pressure may directly damage the small vessels of optic disc and increase the risk of glaucoma.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence of Glaucoma in Type 2 Diabetes Mellitus and Its Relation to Hypertension

Jayalekshmi¹,

P²

2018

jebmh

View full text Add to dashboard Cite

BACKGROUNDGlaucoma is one of the leading global causes of irreversible blindness. Vascular risk factors like hypertension and diabetes can influence the development and progression of glaucoma. Hence, screening for glaucoma is of utmost importance in patients with hypertension and diabetes.The aim of the study is to study the prevalence of glaucoma in type 2 diabetic patients and its relation to systemic hypertension.

show abstract

Determinants for late presentation of glaucoma among adult glaucomatous patients in University of Gondar Comprehensive Specialized Hospital. Case-control study

et al. 2022

View full text Add to dashboard Cite

Introduction Glaucoma is a disease which causes optic nerve damage and remains a major public health concern worldwide. Late presentation is a major risk factor for glaucoma induced blindness. The aim of this study was to assess determinants for late presentation of glaucoma among adult glaucomatous patients. Methods A hospital-based case-control study was conducted among 452 adult glaucomatous patients. Late presenters were glaucoma patients diagnosed with cup to disc ratio (CDR) > 0.8 and mean deviation of greater than -14 decibel in either of the eyes at their first presentation. Study participants were selected among glaucomatous follow-up patients by using systematic random sampling. Data were entered into EPI Info version 7 and exported to SPSS version 22 for analysis. Bivariable and multivariable logistic regression analysis was done to identify determinants. Variables with P-value < 0.05 were considered as statistically significant. Result The mean age of participants were 55.1 ± 13.2 years. Being > 60 years of age, 4.51 times (AOR: 4.51; 95% CI: 1.74, 11.67), resided > 53 km away from the hospital 6.02 times (AOR: 6.02; 2.76, 13.14), Presenting IOP > 30 mmHg, 4.49 times (AOR: 4.49, 95% CI: 2.10, 9.12), poor knowledge of glaucoma, 4.46 times (AOR: 4.46, CI: 2.62, 7.58) and absence of regular eye checkup, 2.35 times (AOR: 2.35, 95% CI: 1.09, 5.47) higher odds of being late presenter. Conclusion Increasing age, high IOP, poor knowledge of glaucoma, residing far away from the hospital and absence of regular eye checkups were significantly associated with late presentation.

show abstract

Study of Ocular Risk Factors for Primary Open-Angle Glaucoma

Cited by 6 publications

References 16 publications

Severity of primary open-angle glaucoma in patients with hypertension and diabetes

Severity of primary open-angle glaucoma in patients with hypertension and diabetes

Prevalence of Glaucoma in Type 2 Diabetes Mellitus and Its Relation to Hypertension

Determinants for late presentation of glaucoma among adult glaucomatous patients in University of Gondar Comprehensive Specialized Hospital. Case-control study

Contact Info

Product

Resources

About