The present investigation deals with the case of an Ag (CuO or Al2O3)-water nanofluid' convection phenomenon within a square enclosure, which including two heated sources, of a square shape. To do so, a computer code, based on the finite volume approach and the SIMPLER algorithm, is adopted to solve the general coupled equations. By studding the impact of some pertinent parameters such the Rayleigh number, the heaters' vertical location within the enclosure, as well as the nanoparticles' volume fraction and its type on the nanofluid flow and heat behaviors, the numerical predictions proved the nanoparticles type is the key factor for the heat transfer enhancement within such industrial geometry, side by side with the increasing function of the Rayleigh number and the nanoparticles' volume fraction. Unlike the latter, the increase in the heaters' vertical location within the enclosure affects the nanofluid flow, but it has no significant impact on the mean transfer rate.