Study of Electrochemical Oxidation of Xanthohumol by Ultra-Performance Liquid Chromatography Coupled to High Resolution Tandem Mass Spectrometry and Ion Mobility Mass Spectrometry

Ambient Pressure Inverse Ion Mobility Spectrometry Coupled to Mass Spectrometry

“…With the added separation dimension afforded by the mobility domain, the combination of ion mobility and mass spectrometry provides a marked improvement in peak capacity, which enables the separation of isomers and, for select systems, the measurement of ion-neutral collisional cross section (ion neutral CCS or Ω). − Hyphenated with chromatography and mass spectrometry, ion mobility spectrometry provides yet another dimension of separation that further enhances separation power and minimizes analysis time. The power and potential of IMS when hyphenated with other analytical methods, such as chromatography and mass spectrometry, has been obvious from the beginning; chromatography separates compounds based on their equilibration between two phases in a time frame of minutes to seconds; ion mobility spectrometry separates ions according to their size/charge ratio in milliseconds; and mass spectrometry separates ions based on their mass/charge ratio in microseconds. − …”