Studies With Functionally Substituted Heteroaromatics: A Novel Route for the Synthesis of 1-Aryl-6-oxopyridazinones, 1-Arylpyridazine-6-imines and 1-Aryl-6-imino-4-pyridazinals

Syntheses of 3,4,7‐triazaacenaphthylene and pyrido[3,4,5‐de]cinnoline derivatives

“…We assume that the initially formed arylazo derivatives hydrolyze to aldehydic arylhydrazono derivatives followed by cyclization. Transformation of an imino to an aldehydic group has been reported under similar reaction condition [10]. Compounds 11a,b reacted with hydrazine hydrate in ethanolic DMF mixture to give the final isolated products 9a,b.…”

Microwave Assisted Condensation Reactions of 2-Aryl Hydrazonopropanals with Nucleophilic Reagents and Dimethyl Acetylenedicarboxylate

“…It has been reported that methylalkyl ketones and methylaryl ketones condense readily with dimethylformamide dimethylacetal (DMFDMA) to yield enaminones, whose chemistry has recently attracted considerable interest [5,6,[12][13][14][15][16][17][18][19][20]. The chemistry of 2-arylhydrazonopropanals has also received considerable interest in the last few years [21][22][23][24][25]. As part of an ongoing project in our laboratory aimed at exploring potential utility of microwave irradiation as a source of heat for producing polyfunctionally substituted heteroaromatics and because of our recent interest in making our synthetic approaches environmentally attractive, we have decided to investigate here the possibility of conducting our reactions in two ways:…”

Studies with enaminones: reactivity of 1,5‐disubstituted‐1,4‐pentadien‐3‐ones toward electrophilic reagents. a novel route to azolylazines, benzofuranals, pyranones

“…In recent work from our laboratories we have successfully utilized enaminones as building blocks for the synthesis of a wide range of heterocycles [4][5][6][7][8]. In conjunction with this work we have investigated possible utility of dienones 1 for synthesis of different otherwise not readily assessable heteroaromatic compounds of potential interest, as agrochemical, pharmaceutical or dye intermediates.…”