Studies on the Relationship of Staphylococcus Aureus to Pseudomembranous Enteritis and to Postantibiotic Enteritis

The pseudomembranous colitis associated with clindamycin therapy--a viral colitis.

“…branous enterocolitis has been frequently reported (Dearing, Baggenstoss, and Weed, 1960;Jackson, Haigh, Kass, Womack, Gocke, and Finland, 1951;Hale and Cosgriff, 1957;Speare, 1954) but is not absolute. There were many patients suffering from pseudomembranous enterocolitis who did not have an intestinal infection that could be attributed to any recognizable bacterial infection but may have been due to inadequate means of identifying certain pathogenic bacteria, and up to 1952 antemortem stool cultures were infrequently performed (Pettet, Baggenstoss, Dearing, and Judd, 1954).…”

The importance of clinicopathological correlation in the diagnosis of inflammatory conditions of the colon: histological patterns with clinical implications

“…The nonspecific pattern of pseudomembranous colitis is usually due to C. difficile, although other toxin-producing bacteria (e.g., verotoxin E. coli 0157) and early or mild ischemia of other cause may induce this pattern (59,60). The pathological features are usually a consequence of relatively weak bacterial toxins that damage the endothelium, producing multiple minute foci of early superficial ischemic necrosis characterized by punctate inflammatory pseudomembranes (42).…”

Το Προβλημα Των Σταφυλοκοκκικων Τροφοδηλητηριασεων

“…Ή νόσος άναπαρήχθη είς Chincillas καί ή τελεία σχέσις μεταξύ του ποσοϋ* της έντεροτοξίνης Β καί της σοβαρότητος τής νόσου απεδείχθη. Έτερα νόσος καλούμενη ψευδομεμβρανώδης έντερϊτις ή έντεροκωλϊτις, ή οποία συνήθως ακο λουθεί τήν δι'αντιβιοτικών θεραπείαν (πενικιλλίνη, στρεπτομυκίνη, τετρακυκλίνη) έχει άρκετήν πειραματικήν ύποστήριξιν δια να θεωρηθή ώς οφειλομένη είς τάς έντεροτοξίνας, παρ' δλον δτι πολλάκις τα κόπρανα είναι αρνητικά δια σταφυλόκοκκους (Dearing et al 1958).…”