Studies on the antioxidant and hepatoprotective activities of polysaccharides from Talinum triangulare

Liang, Dong; Zhou, Qing; Gong, Wenbin; Wang, Yi; Nie, Zhi-Kui; He, Hui; Li, Jiangtao; Wu, Jiahui; Wu, Chenxi; Zhang, Jiu‐liang

doi:10.1016/j.jep.2011.04.047

Cited by 92 publications

(58 citation statements)

References 24 publications

(20 reference statements)

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“…However, excessively generated free radicals free radicals increase the oxidative stress in organisms by causing deleterious effects to cell structures. Many disease conditions like diabetes, inflammation, cancer, atherosclerosis, liver diseases, aging, hypertension, and neurodegenerative diseases precipitate directly or indirectly through reactive oxygen species (ROS)-mediated signal pathways (Liang et al, 2011;Sarwar et al, 2015). Furthermore, oxidative rancidity in foods leads to reduction in its shelf life.…”

Section: Introductionmentioning

confidence: 99%

Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models

Kim¹,

Kim²

2016

TANG [HUMANITAS MEDICINE]

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Oxidative rancidity in foods causes undesirable changes in nutritive value, aroma, flavor, and color. Salix Koreensis Andersson in DC. (SK) has anti-oxidative and anti-inflammatory effects and is traditionally used to treat neuralgia, edema, pain, and inflammatory diseases. However, the regulatory effects of SK on oxidative and inflammatory reactions have not been elucidated. In this context, we scientifically validated the anti-oxidative and anti-inflammatory activities of SK leaf (SKL). The methanol extract of SKL was evaluated for in vitro anti-oxidative activities. SKL showed increased superoxide dismutase (SOD)-like activity and 1, 1-diphenyl-2-picrylhydrazyl radical scavenging activity. The in vitro anti-oxidant and antiinflammatory activities of SKL were also investigated in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. LPS resulted in decreased SOD activities compared with the unstimulated cells, but SKL significantly increased SOD activities reduced by LPS. In addition, LPS-induced nitric oxide, tumor necrosis factor-α, and interleukin-6 productions were significantly and dose-dependently reduced by SKL in RAW264.7 macrophages without inducing cytotoxicity. In conclusion, these results indicate that SKL will be able to be effectively used as a food additive with anti-oxidative and anti-inflammatory effects.

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Section: Introductionmentioning

confidence: 99%

Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models

Kim¹,

Kim²

2016

TANG [HUMANITAS MEDICINE]

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“…Forced swimming tests have been widely used to evaluate the anti-fatigue properties of natural products [25,26]. This method results in less mechanical stress and damage, and a better redistribution of blood flow in the tissues without significant changes in cardiac output and heart rate, which can in turn lead to an amount of damage that is caused by production of ROS [27].…”

Section: Discussionmentioning

confidence: 99%

“…Polysaccharides from P. odoratum were isolated as previously reported [14,16] with small changes. Dried ground samples were extracted with distilled water at 90°C for approximately 2.5 h. The aqueous extract was filtered and centrifuged (2,000 × g for 10 min, at 20°C).…”

Section: Preparation Of Polysaccharides From P Odoratummentioning

confidence: 99%

“…The animals were housed in environmentally controlled conditions (humidity of 55 ± 5 %, temperature of 22 ± 1°C) with a 12:12 hour light:dark cycle. Animal procedures were carried out in accordance with the National Institute of Health Guide for the Care and Use of Laboratory Animals [16], and approved by the Ethics Committee of Yancheng Institute of Technology (approval no. SYLL2015-0211).…”

Section: Experimental Animalsmentioning

confidence: 99%

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Polysaccharides from Polygonatum odoratum strengthen antioxidant defense system and attenuate lipid peroxidation against exhaustive exercise-induced oxidative stress in mice

Yang¹,

Zhang²

2017

Trop. J. Pharm Res

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“…However, the PPG supplementation was able to maintain the SOD activity. It has been proven that the polysaccharides from herbal sources protect the liver injury by enhancing the SOD activity (Gan et al 2012;Liang et al 2011). …”

Section: Discussionmentioning

confidence: 99%

Supplementation of Psidium guajava (Guava) Fruit Polysaccharide Attenuates Paracetamol-induced Liver Injury by Enhancing the Endogenous Antioxidant Activity

Alias¹,

Othman²,

Li³

et al. 2015

JSM

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Studies on the antioxidant and hepatoprotective activities of polysaccharides from Talinum triangulare

Cited by 92 publications

References 24 publications

Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models

Anti-oxidant and anti-inflammatory effects of Salix Koreensis Andersson in DC. leaf methanol extract in vitro models

Polysaccharides from Polygonatum odoratum strengthen antioxidant defense system and attenuate lipid peroxidation against exhaustive exercise-induced oxidative stress in mice

Supplementation of Psidium guajava (Guava) Fruit Polysaccharide Attenuates Paracetamol-induced Liver Injury by Enhancing the Endogenous Antioxidant Activity

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