Studies on the alkaloids of Solanum of northeastern Brazil

Silva, Tania M. Sarmento; Agra, Maria de Fátima; Bhattacharyya, Jnanabrata

doi:10.1590/s0102-695x2005000400005

Cited by 18 publications

(13 citation statements)

References 5 publications

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“…The presence of the steroidal alkaloid solasodine, which is potentially an important starting material for the synthesis of steroid hormones, is characteristic of the genus Solanum (Silva et al, 2005a;Silva et al, 2005b;Barbosa-Filho et al, 1991).…”

Section: Introductionmentioning

confidence: 99%

Brine shrimp bioassay of some species of Solanum from Northestern Brazil

Silva¹,

Nascimento²,

Batista³

et al. 2007

Rev. bras. farmacogn.

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RESUMO: "Bioatividade em Artemia salina de várias espécies de Solanum do Nordeste Brasileiro". Os extratos metanólicos de 13 espécies de Solanum (Solanaceae) foram testados para verififi cação da bioatividade em Artemia salina. As espécies testadas (partes aéreas, raízes e frutos) foram: S. asperum, S. capsicoides, S. palinacantum, S. paludosum, S. paniculatum, S. paraibanum, S. sisymbriifolium, S. crinitum, S. diamantinense, S. megalonyx, S. torvum, S. asterophorum e S. stipulaceum. Das treze espécies testadas, quatro foram inativas. Os extratos dos frutos de S. asperum (CL 50 = 420,5 µg/mL) e S. paludosum (CL 50 = 548,0 µg/mL), partes aéreas de S. diamantinense (CL 50 = 481,0 µg/mL) e S. sisymbrifolium (CL 50 = 382,7 µg/mL), e das raízes S. asperum (CL 50 = 593,4 µg/mL) e S. stipulaceum (CL 50 = 823,1 µg/mL) que mostraram atividade moluscicida contra Biomphalaria glabrata também mostraram atividade tóxica em Artemia salina.Unitermos: Solanaceae, Solanum, Artemia salina, bioatividade. ABSTRACT:The methanolic extracts of 13 Specieis of the genus Solanum (Solanaceae) have been tested for bioactivity in Artemia salina. The extracts investigated were prepared from various parts (aerial parts, roots and fruits) of S. asperum, S. capsicoides, S. palinacantum, S. paludosum, S. paniculatum, S. paraibanum, S. sisymbriifolium, S. crinitum, S. diamantinense, S. megalonyx, S. torvum, S. asterophorum and S. stipulaceum. The lethal concentrations were determined for the extracts and among thirteen plants tested, four appear to be inactive. The extracts of the fruits of S. asperum (LC 50 = 420.5 µg/mL) and S. paludosum (LC 50 = 548.0 µg/mL), aerial parts of S. diamantinense (LC 50 = 481.0 µg/mL) and S. sisymbrifolium (LC 50 = 382.7 µg/mL), and the roots of S. asperum (LC 50 = 593.4 µg/mL) and S. stipulaceum (LC 50 = 823.1 µg/mL), all of which previously showed molluscicidal activity against Biomphalaria glabrata were also found to be active in the present study with brine shrimp.

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Section: Introductionmentioning

confidence: 99%

Brine shrimp bioassay of some species of Solanum from Northestern Brazil

Silva¹,

Nascimento²,

Batista³

et al. 2007

Rev. bras. farmacogn.

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“…(hyoscine). [10] The Solanaceae family also includes ornamental plants, such as petúnias (Petunia spp.) and jasmine (S. jasminoides), and tobacco (Nicotiana tabacum).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activity and Phenolics Analysis by HPLC-DAD of Solanum thomasiifolium Sendtner (Solanaceae)

Magalhães¹,

Cassiano²,

Branco³

et al. 2014

Free Rad. Antiox.

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“…It is rich in steroidal alkaloids as tomatidine (Takagi et al, 1994) and solasodine (Yencho et al, 1998;Barbosa-Filho et al, 1991;Silva et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Morphological, anatomical, macro and micromolecular markers for Solanum cernuum identification

Alves¹,

Marengo²,

Machado³

et al. 2007

Rev. bras. farmacogn.

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RESUMO: "Marcadores morfológicos, anatômicos, macro e micromoleculares para a identifi cação de Solanum cernuum". Plantas consumidas como remédio nem sempre são identifi cadas taxonomicamente de maneira correta. Se estas plantas forem utilizadas para obtenção de uma droga vegetal ou um fi toterápico, tal erro pode afetar a qualidade do produto fi nal. Neste trabalho são descritos marcadores para a identifi cação de Solanum cernuum Vell. (Solanaceae), esteja a planta íntegra, triturada ou como extrato bruto. Indivíduos de quatro localidades de Minas Gerais foram coletados, analisados e comparados. Os caracteres morfológicos foram utilizados para a planta íntegra. Para a planta triturada, o conjunto dos tricomas foi utilizado como marcador anatômico. Um marcador macromolecular também foi determinado. Para tal a região ITS1, 5.8S e ITS2 do DNAr foi clonada e seqüenciada. A seqüência, com cerca de 600 pares de bases dos quais 48,1% são AT, foi depositada no GenBank sob o número de acesso DQ837371. Por ser uma seqüência específi ca para S. cernuum, ela pode ser usada como marcador desta espécie. Para o extrato bruto foram determinados perfi s cromatográfi cos de extratos das folhas por cromatografi a em camada delgada e por cromatografi a líquida de alta efi ciência. Dois fl avonóides foram isolados e identifi cados como quercitrina e afzelina. Assim, neste trabalho foram determinados marcadores morfológicos, anatômicos, macro e micromoleculares para identifi car S. cernuum.Unitermos: Solanum cernuum, Solanaceae, tricomas, quercitrina, afzelina, ITS rDNA. ABSTRACT:The plants consumed as remedy by the population may have imprecise taxonomical identifi cation. If these plants are used for the production of phytomedicines such misidentifi cation may affect the quality of the product. Hereby, we describe markers for identifi cation of the entire plant or grounded plant material or the crude extract of Solanum cernuum Vell. (Solanaceae). Specimens from four localities were collected, analyzed and compared. Morphological characters were used to identify the plant when it is not grounded or extracted. However, when the plant material is grounded, the set of trichomes may be used as anatomical marker. The region ITS1, 5.8S and ITS2 of the nuclear ribosomal DNA was cloned and sequenced. The sequence, with length of about 600 base pairs, being 48.1% AT , was deposited in GenBank under the accession number DQ837371. Once this sequence is specifi c to S. cernuum, it was used as marker for this species. For the crude extract, chromatographic profi les of the leaves extracts were obtained by thin layer chromatography (TLC) and high performance liquid chromatography (HPLC). Two fl avonoids were isolated and identifi ed as quercitrin and afzelin. So, this study presents morphological, anatomical, macro and micromolecular markers to identify S. cernuum.

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Studies on the alkaloids of Solanum of northeastern Brazil

Cited by 18 publications

References 5 publications

Brine shrimp bioassay of some species of Solanum from Northestern Brazil

Brine shrimp bioassay of some species of Solanum from Northestern Brazil

Antioxidant Activity and Phenolics Analysis by HPLC-DAD of Solanum thomasiifolium Sendtner (Solanaceae)

Morphological, anatomical, macro and micromolecular markers for Solanum cernuum identification

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