Studies on Some Psychopharmacological Actions of Moringa oleifera Lam. (Moringaceae) Leaf Extract

Abstract

The methanol extract of the leaves of Moringu oleifera Lam. was investigated for some psychopharmacological actions in animals. The extract was found to produce a significant alteration in general behavioural pattern by head dip test, Y-maze test, evasion test, and reduction in muscle relaxant activity by rotarod test, chimney test and traction test. Beside these, the extract also potentiated pentobarbitone induced sleeping time and lowered body temperature in experimental animals.

Antiobesity and Hypolipidemic Activity ofMoringa oleiferaLeaves against High Fat Diet-Induced Obesity in Rats

“…The lethal dose (LD 50 ) value of the M. oleifera indicated that the extract (methanol) was safe and nontoxic up to 5 g/kg [33,38]. Previous experiments have reported the antiulcer, diuretic, anti-inflammatory, antifertility, CNS depressant, and wound healing properties of leaves of M. oleifera [26,[38][39][40][41]. However, the results of the previous laboratory animal study indicated that crude extract of M. oleifera possesses hypocholesterolemic activity in rats [32].…”

The Medicinal Qualities of Moringa Oleifera

“…In a series of studies with Holtzman strain albino rats, Ray et al 11,12 demonstrated that serotonin in Moringa oleifera potentiated the sleep-inducing properties of phenobarbital. Pal et al 13 found that dried Moringa oleifera leaves significantly potentiated sleep in Swiss albino mice treated with phenobarbital compared with controls (P < .001). Findings also suggested that Moringa oleifera significantly relaxed muscle cramps and reduced body temperature.…”

Use of Laser-Induced Breakdown Spectroscopy for the Detection of Glycemic Elements in Indian Medicinal Plants

“…The leaves of M. oleifera are lopped for fodder [69] and have been used as antiulcer, diuretic, antiinflammatory and for wound healing [67, 70]. Ethanolic extract of leaves has shown antifungal activity against a number of dermatophytes [71, 72]. The aqueous extract of the leaves has been found to possess antidiabetic activity [73].…”