One of our colleagues, S. Kikuchi, has conducted the intravenous glucose tolerance test in patients with various skin diseases as will be published in the Jap. J. of Dermat. in the near future and found that pyodermas, generally speaking, in 41.7% cases showed intolerance to sugar, of which both carbuncles and furuncles in 36.8% and acne vulgaris in 50% showed intolerance to sugar. The pathoglucemic curve obtained in this study is not understood to be prediabetic curve, but as a curve showing disturbance in liver function (Soskin & Levine1)). The acne vulgaris cases that have come under our treatment are 27 in number (6 males and 21 females) and intolerance to sugar are observed in 55.6% of them. Skin sugar was measured in only one of the above, and was recorded as 89 mg/100 g in fasting value, while his blood sugar in fasting showed the value of 98 mg/dl, so that the ratio of skin sugar/blood sugar stood at 90.8%. These figures are not abnormal as compared with the normal values of 89.8 mg/100 g of skin sugar and 89.8% of the ratio between skin and blood sugar in normal Japanese, obtained by Mihara (Fasting value of skin sugar differs from that of Urbach et al.2) " Studies on Skin Sugar in Normal Japanese and Skin Diseases " by Mihara will shortly appear in the Jap. J. of Dermat.). The time of recovery of the starting value of skin sugar following a glucose tolerance test, however, was 226 minutes in this case, a value much in excess of the normal 60 minutes. The recovery time of blood sugar was 38 minutes, a value well within the normal range. From these results, we may conclude that the skin of this patient retains sugar in it for a long time. We must wait for test results with many further cases to speak with some confidence whether such a sugar retention in the skin in acne vulgaris patients is of common occurrence, but this single case suggests something of interest, in con-301