Drug Metabolism Handbook 2022
DOI: 10.1002/9781119851042.ch12
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Studies of Reactive Metabolites using Genotoxicity Arrays and Enzyme/DNABiocolloids – 2021

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“…7,14–19 Cyt P450s are biocatalysts for C–H hydroxylation, N- and S-oxidation, O-, N- and S-dealkylation, C–C bond cleavage, CC double bond epoxidation, aromatic coupling, as well as more unusual reactions. 20,21 They are effective for synthesis of drugs, drug metabolites, 22–27 bioremediation, 28–30 and development of biosensors. 31–33…”
Section: Introductionmentioning
confidence: 99%
“…7,14–19 Cyt P450s are biocatalysts for C–H hydroxylation, N- and S-oxidation, O-, N- and S-dealkylation, C–C bond cleavage, CC double bond epoxidation, aromatic coupling, as well as more unusual reactions. 20,21 They are effective for synthesis of drugs, drug metabolites, 22–27 bioremediation, 28–30 and development of biosensors. 31–33…”
Section: Introductionmentioning
confidence: 99%