Studies in Neonatal Hepatitis and Biliary Atresia

Clinical aspects on neonatal cholestasis based on observations at a Swedish tertiary referral centre

“…Our results also reinforce those of others in that patients with paucity of intrahepatic bile ducts frequently lack excretion on scintigraphy (18). However, arguing against some earlier reports (19), the " unnecessary" laparotomy performed in patients with patent extrahepatic bile ducts did not seem to worsen their prognosis.…”

Clinical aspects on neonatal cholestasis based on observations at a Swedish tertiary referral centre

“…Our results also reinforce those of others in that patients with paucity of intrahepatic bile ducts frequently lack excretion on scintigraphy (18). However, arguing against some earlier reports (19), the " unnecessary" laparotomy performed in patients with patent extrahepatic bile ducts did not seem to worsen their prognosis.…”

Excretion of Bile Acids in Extrahepatic Biliary Atresia and Intrahepatic Cholestasis of Infancy

“…Cholestatic jaundice in infancy is mainly due either to extrahepatic biliary atresia or to intrahepatic cholestasis of infancy ("neonatal hepatitis syndrome"). Differential diagnosis between these conditions may often be difficult in the early stages of cholestasis (5, 27). Practically all available laboratory techniques fail to provide adequate diagnostic information.…”

Clinical aspects on neonatal cholestasis based on observations at a Swedish tertiary referral centre

“…Our results also reinforce those of others in that patients with paucity of intrahepatic bile ducts frequently lack excretion on scintigraphy (18). However, arguing against some earlier reports (19), the " unnecessary" laparotomy performed in patients with patent extrahepatic bile ducts did not seem to worsen their prognosis.…”

Excretion of Bile Acids in Extrahepatic Biliary Atresia and Intrahepatic Cholestasis of Infancy

“…Cholestatic jaundice in infancy is mainly due either to extrahepatic biliary atresia or to intrahepatic cholestasis of infancy ("neonatal hepatitis syndrome"). Differential diagnosis between these conditions may often be difficult in the early stages of cholestasis (5, 27). Practically all available laboratory techniques fail to provide adequate diagnostic information.…”

Clinical aspects on neonatal cholestasis based on observations at a Swedish tertiary referral centre

“…Our results also reinforce those of others in that patients with paucity of intrahepatic bile ducts frequently lack excretion on scintigraphy (18). However, arguing against some earlier reports (19), the " unnecessary" laparotomy performed in patients with patent extrahepatic bile ducts did not seem to worsen their prognosis.…”

Excretion of Bile Acids in Extrahepatic Biliary Atresia and Intrahepatic Cholestasis of Infancy

“…Cholestatic jaundice in infancy is mainly due either to extrahepatic biliary atresia or to intrahepatic cholestasis of infancy ("neonatal hepatitis syndrome"). Differential diagnosis between these conditions may often be difficult in the early stages of cholestasis (5, 27). Practically all available laboratory techniques fail to provide adequate diagnostic information.…”