Structures and reactivities of several iron(III) complexes in the presence of hydrogen peroxide: Relevance to induction of tissue damage caused by iron(III) chelates in rats

Model Reactions for the Formation of Iron Deposition

“…7, No. 1;2015 In addition to the above, we in this study found that zinc(II) ion leads to the iron deposition formation (see Figure 9) (Nishino et al 1999). Remarkably strong power of zinc (II) ion to give iron deposition should be noted !…”

“…K 2 [Fe 2 O(CO 3 )(edda) 2 ], Fe(dpa)Cl 2 , and Fe(dpal)Cl 2 , (Schimitt et al, 2002;Nishida & Ito, 1995;Sutoh, Okawamukai, Nishino, & Nishida, 2006) the chemical structures and their abbreviations of several ligands cited in this paper being illustrated in Figure 1.…”

Model Reactions for the Formation of Iron Deposition

“…7, No. 1;2015 In addition to the above, we in this study found that zinc(II) ion leads to the iron deposition formation (see Figure 9) (Nishino et al 1999). Remarkably strong power of zinc (II) ion to give iron deposition should be noted !…”

“…K 2 [Fe 2 O(CO 3 )(edda) 2 ], Fe(dpa)Cl 2 , and Fe(dpal)Cl 2 , (Schimitt et al, 2002;Nishida & Ito, 1995;Sutoh, Okawamukai, Nishino, & Nishida, 2006) the chemical structures and their abbreviations of several ligands cited in this paper being illustrated in Figure 1.…”

Achieving Selectivity for Phosphate over Pyrophosphate in Ethanol with Iron(III)-Based Fluorescent Probes

“…Both of those observations are attributable to coordination of orthophosphate to the strongly paramagnetic Fe III center. 45,46 Of note, the presence of a single peak in the 31 P also suggests the presence of a rapid equilibrium between bound and free phosphate. Fe III -HOPO-PhO-fluo (2), which employs a pentadentate ligand, displays similar behavior with the coordination of phosphate to the Fe III center confirmed from both the ATR-IR and the 31 P NMR spectra (Figures S7 and S8, respectively).…”

The chemical mechanism of oxidative stress by copper(II) and iron(III) ions in several neurodegenerative disorders

“…On the basis of the spectral studies on the solution containing an iron(III) compound and hydrogen peroxide, we found that in the presence of hydrogen peroxide the Fe-(nta) complex facilely gives a (m-1 : 1 )-peroxodiiron (III)-(nta) species shown in Scheme 5 [20,62,65], which exhibits high reactivity similar to that of singlet oxygen ( 1 D g ) [66][67][68]. However, no formation of (m-1 : 1 )-peroxodiiron(III) species occurs in the solution of Fe-(pac) complex in the presence of hydrogen peroxide.…”

Model Reactions for the Formation of Iron Deposition

“…7, No. 1;2015 In addition to the above, we in this study found that zinc(II) ion leads to the iron deposition formation (see Figure 9) (Nishino et al 1999). Remarkably strong power of zinc (II) ion to give iron deposition should be noted !…”

“…K 2 [Fe 2 O(CO 3 )(edda) 2 ], Fe(dpa)Cl 2 , and Fe(dpal)Cl 2 , (Schimitt et al, 2002;Nishida & Ito, 1995;Sutoh, Okawamukai, Nishino, & Nishida, 2006) the chemical structures and their abbreviations of several ligands cited in this paper being illustrated in Figure 1.…”

Achieving Selectivity for Phosphate over Pyrophosphate in Ethanol with Iron(III)-Based Fluorescent Probes

“…Both of those observations are attributable to coordination of orthophosphate to the strongly paramagnetic Fe III center. 45,46 Of note, the presence of a single peak in the 31 P also suggests the presence of a rapid equilibrium between bound and free phosphate. Fe III -HOPO-PhO-fluo (2), which employs a pentadentate ligand, displays similar behavior with the coordination of phosphate to the Fe III center confirmed from both the ATR-IR and the 31 P NMR spectra (Figures S7 and S8, respectively).…”

The chemical mechanism of oxidative stress by copper(II) and iron(III) ions in several neurodegenerative disorders

“…On the basis of the spectral studies on the solution containing an iron(III) compound and hydrogen peroxide, we found that in the presence of hydrogen peroxide the Fe-(nta) complex facilely gives a (m-1 : 1 )-peroxodiiron (III)-(nta) species shown in Scheme 5 [20,62,65], which exhibits high reactivity similar to that of singlet oxygen ( 1 D g ) [66][67][68]. However, no formation of (m-1 : 1 )-peroxodiiron(III) species occurs in the solution of Fe-(pac) complex in the presence of hydrogen peroxide.…”

Model Reactions for the Formation of Iron Deposition

“…7, No. 1;2015 In addition to the above, we in this study found that zinc(II) ion leads to the iron deposition formation (see Figure 9) (Nishino et al 1999). Remarkably strong power of zinc (II) ion to give iron deposition should be noted !…”

“…K 2 [Fe 2 O(CO 3 )(edda) 2 ], Fe(dpa)Cl 2 , and Fe(dpal)Cl 2 , (Schimitt et al, 2002;Nishida & Ito, 1995;Sutoh, Okawamukai, Nishino, & Nishida, 2006) the chemical structures and their abbreviations of several ligands cited in this paper being illustrated in Figure 1.…”

Achieving Selectivity for Phosphate over Pyrophosphate in Ethanol with Iron(III)-Based Fluorescent Probes

“…Both of those observations are attributable to coordination of orthophosphate to the strongly paramagnetic Fe III center. 45,46 Of note, the presence of a single peak in the 31 P also suggests the presence of a rapid equilibrium between bound and free phosphate. Fe III -HOPO-PhO-fluo (2), which employs a pentadentate ligand, displays similar behavior with the coordination of phosphate to the Fe III center confirmed from both the ATR-IR and the 31 P NMR spectra (Figures S7 and S8, respectively).…”

The chemical mechanism of oxidative stress by copper(II) and iron(III) ions in several neurodegenerative disorders

“…On the basis of the spectral studies on the solution containing an iron(III) compound and hydrogen peroxide, we found that in the presence of hydrogen peroxide the Fe-(nta) complex facilely gives a (m-1 : 1 )-peroxodiiron (III)-(nta) species shown in Scheme 5 [20,62,65], which exhibits high reactivity similar to that of singlet oxygen ( 1 D g ) [66][67][68]. However, no formation of (m-1 : 1 )-peroxodiiron(III) species occurs in the solution of Fe-(pac) complex in the presence of hydrogen peroxide.…”