Structural insights into glutathione-protected gold Au10−12(SG)10−12 nanoclusters revealed by ion mobility mass spectrometry

Comby‐Zerbino, Clothilde; Bertorelle, Franck; Chirot, Fabien; Dugourd, Philippe; Antoine, Rodolphe

doi:10.1140/epjd/e2018-90133-8

Cited by 15 publications

(14 citation statements)

References 28 publications

(34 reference statements)

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“…A combined ion mobility-mass spectrometry approach was used in reference [37] for the analysis of ultrasmall gold nanoclusters protected by glutathione (SG) ligands. SG-coated gold nanoclusters have been suggested as potential radiosensitizers for radiation therapy [60].…”

Section: Atomic Clusters and Complex Molecular Systems As Radiosensitmentioning

confidence: 99%

“…SG-coated gold nanoclusters have been suggested as potential radiosensitizers for radiation therapy [60]. Collision cross section (CCS) measurements were reported in [37] for different charge states of Au 10 (SG) 10 , Au 11 (SG) 11 and Au 12 (SG) 12 . Semi-empirical calculations at the PM7 level of theory were performed to optimize geometrical structures of the clusters and use them to compute CCS.…”

Section: Atomic Clusters and Complex Molecular Systems As Radiosensitmentioning

confidence: 99%

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Topical Issue on atomic cluster collisions

et al. 2019

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The rapidly emerging field of atomic cluster collisions attracts strong research interest of many experimental and theoretical groups worldwide. Being a highly interdisciplinary field, it has numerous links with atomic, molecular and optical physics, astrophysics, plasma physics, biophysics, physical chemistry, solid state physics and even molecular biology. This Topical Issue presents a state-of-the-art description of current research activities in the field of atomic cluster collisions and atomic cluster science. The contributions to this Issue represent experimental, theoretical and computational studies both at the fundamental level of elementary mechanisms and at a more applied level which is necessary in numerous applications of nano-and biotechnology, materials science and medicine.

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Section: Atomic Clusters and Complex Molecular Systems As Radiosensitmentioning

confidence: 99%

Section: Atomic Clusters and Complex Molecular Systems As Radiosensitmentioning

confidence: 99%

Topical Issue on atomic cluster collisions

et al. 2019

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“…As a complement to these powder-based structural characterization techniques requiring X-ray beams or synchrotron facilities, mass spectrometry-based techniques performed on gas phase nanoclusters ions may provide information on 3D molecular structures. In particular, ion mobility spectrometry (IMS) has been used for the characterization of gas-phase ligand-protected metal nanoclusters [12,13,14,15,16,17,18,19]. IMS separation is based on the different velocities adopted by ions travelling in an inert gas under a low electric field.…”

Section: Introductionmentioning

confidence: 99%

“…The drift time of the ions through the IMS tube depends on the ratio between their collision cross-section (CCS) with the gas and their charge, thus allowing isomer discrimination. Our groups showed how IMS studies can provide insight into the size of glutathione-protected gold nanoclusters, as well as in the structural determination of inorganic nanoclusters [16,18,19].…”

Section: Introductionmentioning

confidence: 99%

“…In a previous recent work, we reported an ion mobility-mass spectrometry (IM-MS) approach for the analysis of homoleptic Au 10-12 (SG) 10-12 nanoclusters. CCS measurements were reported for different charge states for Au 10 (SG) 10 , Au 11 (SG) 11 , and Au 12 (SG) 12 nanoclusters [18]. Strong charge-state effects on experimental CCS values were observed and attributed to charge-induced glutathione unfolding.…”

Section: Introductionmentioning

confidence: 99%

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Catenane Structures of Homoleptic Thioglycolic Acid-Protected Gold Nanoclusters Evidenced by Ion Mobility-Mass Spectrometry and DFT Calculations

et al. 2019

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Thiolate-protected metal nanoclusters have highly size- and structure-dependent physicochemical properties and are a promising class of nanomaterials. As a consequence, for the rationalization of their synthesis and for the design of new clusters with tailored properties, a precise characterization of their composition and structure at the atomic level is required. We report a combined ion mobility-mass spectrometry approach with density functional theory (DFT) calculations for determination of the structural and optical properties of ultra-small gold nanoclusters protected by thioglycolic acid (TGA) as ligand molecules, Au10(TGA)10. Collision cross-section (CCS) measurements are reported for two charge states. DFT optimized geometrical structures are used to compute CCSs. The comparison of the experimentally- and theoretically-determined CCSs allows concluding that such nanoclusters have catenane structures.

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