Structural and functional imaging in children with partial epilepsy

EEG Source Imaging in Pediatric Epilepsy Surgery: A New Perspective in Presurgical Workup

“…The yield of ESI compared favorably with that of PET (82%) and was superior to that of ictal SPECT (70%). The proportions of correct PET or SPECT localization, respectively, correspond to that described in other studies [i.e., our patient population is similar to those investigated elsewhere (59–67)]. Given the costs of these imaging procedures, ESI represents an interesting alternative.…”

EEG Source Imaging in Pediatric Epilepsy Surgery: A New Perspective in Presurgical Workup

“…The yield of ESI compared favorably with that of PET (82%) and was superior to that of ictal SPECT (70%). The proportions of correct PET or SPECT localization, respectively, correspond to that described in other studies [i.e., our patient population is similar to those investigated elsewhere (59–67)]. Given the costs of these imaging procedures, ESI represents an interesting alternative.…”

Magnetocephalography: a noninvasive alternative to the Wada procedure

“…With recent improvements in the sampling density of magnetic sensors, it is now possible reliably to record and model brain activity associated with the engagement of anterior language areas in the performance of expressive tasks (such as word-fluency and picture-naming tasks). Brain activation protocols that target these regions have been successfully used in the context of hemodynamic imaging methods 1,12,17 and are expected to complement existing protocols to further increase the selectivity of MEG-derived estimates of hemispheric dominance for language function. Accumulated experience with the study of more than 240 patients and 100 healthy control volunteers who had undergone presurgical language mapping by using identical procedures prompted a number of revisions in the MEG data analysis procedures to ensure data integrity.…”

“…Although most published studies on comparisons between brain imaging and Wada estimates of hemispheric dominance for language have generally shown concordance, discordance has been reported in 5 to 10% of the cases. 12,13,40 Language-mapping protocols have been developed concurrently by using MEG to record event-related brain activity. Initial studies conducted by at least two research groups reported excellent concordance with results of the Wada test in adults 4,22 and children, 3 on a patient-by-patient basis.…”

Organization of language networks in children: Functional magnetic resonance imaging studies

“…In addition, this technique can be employed in patient populations such as epileptic children [36][37][38], children with autism [39,40], or dyslexic children [29•,30-34]. Data from studies of language processing in normal children show that they employ similar brain areas as adults when performing tasks of fluency, auditory comprehension, reading, and phonemic and semantic judgement tasks.…”

EEG Source Imaging in Pediatric Epilepsy Surgery: A New Perspective in Presurgical Workup

“…The yield of ESI compared favorably with that of PET (82%) and was superior to that of ictal SPECT (70%). The proportions of correct PET or SPECT localization, respectively, correspond to that described in other studies [i.e., our patient population is similar to those investigated elsewhere (59–67)]. Given the costs of these imaging procedures, ESI represents an interesting alternative.…”

Magnetocephalography: a noninvasive alternative to the Wada procedure

“…With recent improvements in the sampling density of magnetic sensors, it is now possible reliably to record and model brain activity associated with the engagement of anterior language areas in the performance of expressive tasks (such as word-fluency and picture-naming tasks). Brain activation protocols that target these regions have been successfully used in the context of hemodynamic imaging methods 1,12,17 and are expected to complement existing protocols to further increase the selectivity of MEG-derived estimates of hemispheric dominance for language function. Accumulated experience with the study of more than 240 patients and 100 healthy control volunteers who had undergone presurgical language mapping by using identical procedures prompted a number of revisions in the MEG data analysis procedures to ensure data integrity.…”

“…Although most published studies on comparisons between brain imaging and Wada estimates of hemispheric dominance for language have generally shown concordance, discordance has been reported in 5 to 10% of the cases. 12,13,40 Language-mapping protocols have been developed concurrently by using MEG to record event-related brain activity. Initial studies conducted by at least two research groups reported excellent concordance with results of the Wada test in adults 4,22 and children, 3 on a patient-by-patient basis.…”

Organization of language networks in children: Functional magnetic resonance imaging studies

“…In addition, this technique can be employed in patient populations such as epileptic children [36][37][38], children with autism [39,40], or dyslexic children [29•,30-34]. Data from studies of language processing in normal children show that they employ similar brain areas as adults when performing tasks of fluency, auditory comprehension, reading, and phonemic and semantic judgement tasks.…”

EEG Source Imaging in Pediatric Epilepsy Surgery: A New Perspective in Presurgical Workup

“…The yield of ESI compared favorably with that of PET (82%) and was superior to that of ictal SPECT (70%). The proportions of correct PET or SPECT localization, respectively, correspond to that described in other studies [i.e., our patient population is similar to those investigated elsewhere (59–67)]. Given the costs of these imaging procedures, ESI represents an interesting alternative.…”

Magnetocephalography: a noninvasive alternative to the Wada procedure

“…With recent improvements in the sampling density of magnetic sensors, it is now possible reliably to record and model brain activity associated with the engagement of anterior language areas in the performance of expressive tasks (such as word-fluency and picture-naming tasks). Brain activation protocols that target these regions have been successfully used in the context of hemodynamic imaging methods 1,12,17 and are expected to complement existing protocols to further increase the selectivity of MEG-derived estimates of hemispheric dominance for language function. Accumulated experience with the study of more than 240 patients and 100 healthy control volunteers who had undergone presurgical language mapping by using identical procedures prompted a number of revisions in the MEG data analysis procedures to ensure data integrity.…”

“…Although most published studies on comparisons between brain imaging and Wada estimates of hemispheric dominance for language have generally shown concordance, discordance has been reported in 5 to 10% of the cases. 12,13,40 Language-mapping protocols have been developed concurrently by using MEG to record event-related brain activity. Initial studies conducted by at least two research groups reported excellent concordance with results of the Wada test in adults 4,22 and children, 3 on a patient-by-patient basis.…”

Organization of language networks in children: Functional magnetic resonance imaging studies

“…In addition, this technique can be employed in patient populations such as epileptic children [36][37][38], children with autism [39,40], or dyslexic children [29•,30-34]. Data from studies of language processing in normal children show that they employ similar brain areas as adults when performing tasks of fluency, auditory comprehension, reading, and phonemic and semantic judgement tasks.…”