volume 32, issue 40, P10692-10699 1993
DOI: 10.1021/bi00091a020
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Yuichiro J. Suzuki, Masahiko Tsuchiya, Stephen R. Wassall, Yuen M. Choo, Girjesh Govil, Valerian E. Kagan, Lester Packer

Abstract: d-alpha-Tocopherol and d-alpha-tocotrienol are two vitamin E constituents having the same aromatic chromanol "head" but different hydrocarbon "tails". alpha-Tocotrienol has been shown to be more potent in protecting against free radical-induced oxidative stress than alpha-tocopherol. Simple models of phospholipid membrane systems were used to investigate the mechanism of the antioxidant potency of alpha-tocotrienol in terms of its effects on membrane order and reorientation dynamics. Chemiluminescence and fluo…

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