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Cited by 82 publications
(88 citation statements)
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“…Among the common helminth parasites known to establish chronic infections in humans, Strongyloides stercoralis, the causative agent of strongyloidiasis, infects over 50 million people worldwide (1). S. stercoralis is unique in its ability to exist in a free-living and auto-infective cycle (2,3). Strongyloides infection is often clinically asymptomatic and long lasting due, in large part, to the parasites' auto-infective life cycle and their ability to modulate or evade the host immune system (2,3).…”
mentioning
confidence: 99%
See 1 more Smart Citation
“…Among the common helminth parasites known to establish chronic infections in humans, Strongyloides stercoralis, the causative agent of strongyloidiasis, infects over 50 million people worldwide (1). S. stercoralis is unique in its ability to exist in a free-living and auto-infective cycle (2,3). Strongyloides infection is often clinically asymptomatic and long lasting due, in large part, to the parasites' auto-infective life cycle and their ability to modulate or evade the host immune system (2,3).…”
mentioning
confidence: 99%
“…S. stercoralis is unique in its ability to exist in a free-living and auto-infective cycle (2,3). Strongyloides infection is often clinically asymptomatic and long lasting due, in large part, to the parasites' auto-infective life cycle and their ability to modulate or evade the host immune system (2,3). Chronic Strongyloides infection can also cause cutaneous, gastrointestinal (GI), and/or pulmonary symptoms and, in the face of immune suppression, may present as hyperinfection syndrome or disseminated strongyloidiasis, conditions that are potentially fatal (4).…”
mentioning
confidence: 99%
“…Among the common helminth parasites known to establish chronic infections in humans, Strongyloides stercoralis, the causative agent of strongyloidiasis (12), is unique in its ability to exist in free-living and autoinfective cycles (13,14), with the latter allowing persistent long-lived infection. Chronic S. stercoralis infection, although commonly clinically silent, can cause cutaneous, gastrointestinal, and/or pulmonary symptoms and, in the face of immune suppression, may present as hyperinfection syndrome or disseminated strongyloidiasis, conditions that are potentially fatal (15).…”
mentioning
confidence: 99%
“…Wild-born great apes develop clinical signs of oesophagostomosis as soon as they are detained in captivity while the presence of the same parasites often remains asymptomatic in wild animals [Krief et al, 2008]. The large majority of humans infected with Strongyloides do not develop any symptom but some people may develop abdominal pain, bloating, heartburn, intermittent episodes of diarrhoea and constipation, a dry cough, and rashes [Toledo et al, 2015;Centers for Disease Control and Prevention, 2016c]. These parasites are also known to cause pulmonary and intestinal injuries in non-human primates and can even lead to a lethal infection in some individuals [Mati et al, 2014].…”
Section: Introductionmentioning
confidence: 99%