Life Cycle and Modes of InfectionAscarislumbricoides transmission to humans is through direct fecal-oral transmission. It occurs mainly with soil contamination of hands or ingestion of contaminated foods or drinks containing mature second-stage larvated (embryonated) eggs. After hatching in the upper part of the small intestine, larvae penetrate the wall of intestinal mucosa, and transport to the vascular capillaries, then via the portal vein to the hepatic circulation. Some of the larvae can migrate to the liver directly through the intestinal wall. Larvae will