Stress responses to repeated exposure to a combined physical and social evaluative laboratory stressor in young healthy males

Boyle, N.B.; Lawton, Clare; Arkbåge, Karin; West, Sheila G.; Thorell, Lars‐Håkan; Hofman, Denise; Weeks, AD; Myrissa, Kyriaki; Croden, Fiona; Dye, Louise

doi:10.1016/j.psyneuen.2015.09.025

Cited by 30 publications

(30 citation statements)

References 53 publications

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“…Our finding that cortisol responses were robust and regular across testing days is in line with recent studies, using a physical stressor combined with elements of social evaluative feedback that also found no indication of habituation effects (Minkley et al, 2014;Boyle. et al, 2016).…”

Section: Discussionsupporting

confidence: 92%

“…Psychological stressors involve the prefrontal cortex (PFC) that in turn activates the HPA axis via connections with limbic structures, while physical stressors tend to rapidly activate the ANS via 1 Notably, our definition of response habituation is in line with (Minkley et al, 2014;Boyle et al, 2016), but broader than the one proposed by some authors who distinguish habituation from negative HPA axis feedback processes and associative learning, as mechanisms leading to a decline in HPA reactivity (see Grissom & Bhatnagar, 2009). reflexive mechanisms in brainstem and hypothalamus (Herman et al 2003;Ulrich-Lai & Herman, 2009).…”

Section: Introductionmentioning

confidence: 93%

“…While the above-mentioned findings derive from studies with either a physical or a psychological stressor, it has been suggested that a stress procedure that combines both physical and psychological elements might be more robust against habituation and sensitization, as it utilizes two pathways rather than just one to stimulate the HPA axis (Minkley et al, 2014;Boyle et al, 2016). Therefore, the present study examined habituation and sensitization to the previously validated Maastricht Acute Stress Test (MAST; Smeets et al, 2012).…”

Section: Introductionmentioning

confidence: 97%

“…In addition to habituation, sensitization effects can emerge due to stress anticipation, i.e. the initiation of stress responses before the actual confrontation with the stressor (Kirschbaum et al, 1995;Preston et al, 2007;Boyle et al, 2016). Evidence for sensitization effects has been found with several widely-used stress paradigms.…”

Section: Introductionmentioning

confidence: 99%

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Examining habituation and sensitization across repetitive laboratory stress inductions using the MAST

Quaedflieg

Meyer

Ruitenbeek

et al. 2017

Psychoneuroendocrinology

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Reliably eliciting acute stress repeatedly over time is of indispensable value for research into stress vulnerability and for developing interventions aimed at increasing stress resiliency. Here, we evaluated whether the Maastricht Acute Stress Test (MAST), a potent stress protocol that combines physical and psychosocial stress components, can be used to reliably elicit subjective and neuroendocrine stress responses multiple times. Sixty healthy undergraduate participants were exposed to the MAST on three occasions, with intervals of three-weeks and one-month in between sessions. Results showed no significant signs of habituation or sensitization to the MAST in terms of subjective or physiological (salivary alpha-amylase and cortisol) stress reactivity. Fifty-nine percent of the sample displayed a significant physiological stress response (i.e., cortisol) to two MAST exposures and 57% to every MAST exposure. This study demonstrates that the MAST can be used to repeatedly induce significant stress responses.

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Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 93%

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Examining habituation and sensitization across repetitive laboratory stress inductions using the MAST

Quaedflieg

Meyer

Ruitenbeek

et al. 2017

Psychoneuroendocrinology

View full text Add to dashboard Cite

show abstract

“…3) is in agreement with the previous evidence that repeated or chronic exposure to stress easily leads to habituation in hypothalamic-pituitary-adrenal (HPA) axis 41,42) but may enhance HPA responses to a novel stressor. 43,44) The HPA sensitization after chronic stress including SART stress may be associated with a reduced efficacy of negative glucocorticoid feedback 45) and involve neurochemical alterations including extracellular signal-regulated kinase (ERK) activation in the hippocampus.…”

Section: Discussionsupporting

confidence: 91%

Repeated Cold Stress Enhances the Acute Restraint Stress-Induced Hyperthermia in Mice

Miyamoto

Funakami

Kawashita

et al. 2017

Biological & Pharmaceutical Bulletin

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The rodents exposed to repeated cold stress according to a specific schedule, known as specific alternation of rhythm in temperature (SART), exhibit autonomic imbalance, and is now used as an experimental model of fibromyalgia. To explore the susceptibility of SART-stressed animals to novel acute stress, we tested whether exposure of mice to SART stress for 1 week alters the extent of acute restraint stress-induced hyperthermia. Mice were subjected to 7-d SART stress sessions; i.e., the mice were alternately exposed to 24 and 4°C at 1-h intervals during the daytime (09:00-16:00) and kept at 4°C overnight (16:00-09:00). SARTstressed and unstressed mice were exposed to acute restraint stress for 20-60 min, during which rectal temperature was monitored. Serum corticosterone levels were measured before and after 60-min exposure to restraint stress. SART stress itself did not alter the body temperature or serum corticosterone levels in mice. Acute restraint stress increased the body temperature and serum corticosterone levels, both responses being greater in SART-stressed mice than unstressed mice. The enhanced hyperthermic responses to acute restraint stress in SART-stressed mice were significantly attenuated by SR59230A, a β 3 adrenoceptor antagonist, but unaffected by diazepam, an anxiolytic, mifepristone, a glucocorticoid receptor antagonist, or indomethacin, a cyclooxygenase inhibitor. These results suggest that SART stress enhances the susceptibility of mice to acute restraint stress, characterized by increased hyperthermia and corticosterone secretion, and that the increased hyperthermic responses to acute stress might involve accelerated activation of sympathetic β 3 adrenoceptors, known to regulate non-shivering thermogenesis in the brown adipose tissue.

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Bilingual family communication and the impact of language anxiety on cortisol reactivity

Legatzke

Gettler

2020

American J Hum Biol

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Objectives The effects of socially evaluated tasks on stress‐related behavior and physiology are often studied under artificial experimental conditions, such as contrived public speaking. Less is known about these behavioral and physiological dimensions under more routine conditions, such as family interactions. Here, we tested whether language anxiety during bilingual family conversations correlated to cortisol reactivity and speech patterns and whether family members' ages moderated this effect. Methods Individuals (N = 34) from Spanish‐English bilingual families participated in prompted conversations in both languages with their family members and provided saliva that we assayed for cortisol. Participants responded to a survey about language anxiety, and we analyzed their conversations for code switching. We tested whether higher reported anxiety was correlated with increased cortisol reactivity and if participants' age moderated this effect. Results Participants' reported language anxiety was not significantly correlated with cortisol reactivity after conversations in either language. However, age significantly moderated the effect of English language anxiety. Among younger individuals, higher English language anxiety was correlated with greater cortisol reactivity after the English conversations. Older individuals did not demonstrate this same pattern. Individuals who code‐switched during the English conversations had higher English language anxiety than individuals who did not. Similar patterns were not observed for the Spanish conversations. Conclusions The physiological and verbal responses to English language anxiety may be reflective of the high pressure placed on English use among bilingual families in the U.S., and the greater cortisol reactivity of younger individuals suggests they may face more identity challenging acculturation pressure.

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Stress responses to repeated exposure to a combined physical and social evaluative laboratory stressor in young healthy males

Cited by 30 publications

References 53 publications

Examining habituation and sensitization across repetitive laboratory stress inductions using the MAST

Examining habituation and sensitization across repetitive laboratory stress inductions using the MAST

Repeated Cold Stress Enhances the Acute Restraint Stress-Induced Hyperthermia in Mice

Bilingual family communication and the impact of language anxiety on cortisol reactivity

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