Storm promotes the dissemination of antibiotic resistome in an urban lagoon through enhancing bio-interactions

Antibiotic resistance in urban stormwater: a review of the dissemination of resistance elements, their impact, and management opportunities

“…For instance, in one study of a coastal lagoon, nutrient concentrations were found to be positively correlated with ARG relative concentration. 100 Nutrient concentrations, as well as other pollutants such as metals, cations, solids, temperature, and conductivity, can be spatially and seasonally dependent. Further research should concentrate on investigating the influence of environmental factors and drainage area characteristics over the composition and persistence of resistance elements in downstream water bodies to provide perspective on the fate of ARGs under varying conditions.…”

“…Consequently, researchers have focused on understanding the effects antibiotic resistance elements in stormwater can have on ecological functioning and human health by sampling water bodies receiving urban stormwater runoff (Table 2). 48,51,53,54,56,58,59,61,[89][90][91][92][93][94][95][96][97][98][99][100][101] Environments that receive direct inputs, such as rivers, estuaries, and lakes, have been described during, immediately after, and after an extended period following rainfall events. Conflicting results of ARG abundances during rainfall have been reported.…”

“…The impacts to downstream water bodies have also been shown to be persistent (>24 hours after rainfall). Concentrations of ARGs are typically highest one day following rainfall and decrease with time, 100 but ARG abundances have been observed to remain elevated above baseline conditions for three weeks, 95 one week, 93 and five days. 61 Moreover, following a significant flooding event, ARG concentrations remained elevated for 10-months while the profile of ARGs as determined through metagenomic sequencing never returned to a preflood state.…”