Stimuli‐Responsive Materials: The Role of Electrostatics and Temperature on Morphological Transitions of Hydrogel Nanostructures Self‐Assembled by Peptide Amphiphiles Via Molecular Dynamics Simulations (Adv. Healthcare Mater. 10/2013)

Abstract

Peptide amphiphiles self‐assemble into nanostructures as either cylindrical nanofibers or spherical micelles in response to specific physiological stimuli. Such morphological transition is captured by large‐scale molecular dynamics simulations in examining spontaneous selfassembly starting from random configurations. , the simulation study by Hung D. Nguyen and co‐workers can potentially aid the design and development of bio‐inspired materials for drug delivery, diagnostic medicine, tissue engineering, and regenerative medicine.