Stilbenes: Quantitative extraction from grape skins, contribution of grape solids to wine and variation during wine maturation

Sun, Baoshan; Ribes, Ana M.; Leandro, M. Conceição; Belchior, A. Pedro; Spranger, M. Isabel

doi:10.1016/j.aca.2005.12.002

Cited by 160 publications

(142 citation statements)

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“…Os estilbenos são comuns em Gnetaceae, Dipterocarpaceae e Vitaceae (Khan et al, 1986). O resveratrol é encontrado em várias plantas (Hart, 1981), mas uvas e produtos relacionados são consideradas as fontes mais importantes, e nelas o teor desse composto depende da variedade e das condições ecológicas do cultivo (Kallithraka et al, 2001;Sun et al, 2006). São precursores das viniferinas, fi toalexinas produzidas em folhas de Vitis vinifera L. (Stecher et al, 2001 Figura 5.…”

Section: Resultsunclassified

Biciclogermacreno, resveratrol e atividade antifúngica em extratos de folhas de Cissus verticillata (L.) Nicolson & Jarvis (Vitaceae)

Silva¹,

Oniki²,

Agripino³

et al. 2007

Rev. bras. farmacogn.

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RESUMO:Cissus verticillata L. (Vitaceae) tem sido empregada popularmente como antidiabética. Nessa espécie foi também detectada atividade fungitóxica. O objetivo do presente trabalho foi realizar a identifi cação dos compostos fungitóxicos em extratos de folhas. O extrato etanólico foi submetido a fracionamento com solventes de diferentes polaridades (hexano, clorofórmio, acetato de etila e butanol) e seu efeito antifúngico foi analisado frente a Cladosporium sphaerospermum. Os extratos em clorofórmio e acetato de etila mostraram atividade, e foram fracionados por cromatografi a em coluna e cromatografi a preparativa em placas de sílica, respectivamente. Três terpenóides foram isolados do extrato em clorofórmio; um deles foi identifi cado, por análise em CG-EM, como um sesquiterpeno, o biciclogermacreno. O composto ativo do extrato em acetato de etila foi identifi cado, por análises em CLAE, como o estilbeno resveratrol.Unitermos: Cissus verticillata, Vitaceae, atividade fungitóxica, sesquiterpeno, estilbeno.ABSTRACTS: "Bicyclogermacrene, resveratrol and fungitoxic activity on leaves extracts of Cissus verticillata L. Nicolson & Jarvis (Vitaceae)". Cissus verticillata L. (Vitaceae) is popularly employed as hypoglicemic and it shows fungitoxic activity. This work aims at identifi cation of fungitoxic compounds on extracts of leaves. The ethanol extract was partitioned using solvents of different polarities (hexane, chloroform, ethyl acetate and butanol) and its fungitoxic activity was analysed upon Cladosporium sphaerospermum. The chloroform and ethyl acetate extracts showed activity and they were fractionated by column chromatography and preparative TLC, respectively. Three terpenoids were isolated from the chloroform extract, one of them identifi ed by GLC-MS analysis as sesquiterpene bicyclogermacrene. The active compound of the ethyl acetate extract was identifi ed by HPLC analyses as stilbene resveratrol.

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Section: Resultsunclassified

Biciclogermacreno, resveratrol e atividade antifúngica em extratos de folhas de Cissus verticillata (L.) Nicolson & Jarvis (Vitaceae)

Silva¹,

Oniki²,

Agripino³

et al. 2007

Rev. bras. farmacogn.

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“…It is well known that the highest concentrations of stilbenes are in berries seeds and skins (Sun et al 2006;Babazadeh et al 2017). The amount of Eresveratrol in grape skin is approximately three times higher than in pulp (Babazadeh et al 2017).…”

Section: Isolation and Identification Of Stilbenes In Edible Berriesmentioning

confidence: 99%

“…Basing on the analysed works (Table 1), the most often used solvent for the extraction process is methanol or the mixtures of methanol with other solvents. In the research conducted by Sun et al (2006) and Romero et al (2001) the influence of extraction solvents on the amount of …”

Section: Isolation and Identification Of Stilbenes In Edible Berriesmentioning

confidence: 99%

“…Many analytical methods with various detection techniques are reported for the separation and identification of individual stilbenes in edible berries, such as liquid chromatography-tandem mass spectrometry (LC-MS/MS) (Vrhovsek et al 2012), liquid chromatography-mass spectrometry (LC-MS) (Može et al 2011), liquid chromatography with dual detection by a photodiode array and quadrupole time-of-flight mass spectrometry (LC-PDA-QTOF/MS) (Samoticha et al 2017), high-pressure liquid chromatography-mass spectrometry (HPLC-MS) (Bavaresco et al 2002;Jiang et al 2012;Kiselev et al 2017), high-pressure liquid chromatography with diode array detection (HPLC-DAD) (Bavaresco et al 2002;Sun et al 2006;Vilanova et al 2015;Guerrero et al 2010aGuerrero et al , 2016, high-pressure liquid chromatography with UV detection (HPLC-UV) (Vincenzi et al 2013;Kawakami et al 2014;He et al 2009a), ultra-high-pressure liquid chromatography quadrupole time-of-flight mass spectrometry (UHPLC/QTOF/MS) (Flamini et al 2016;De Rosso et al 2016), ultra-performance liquid chromatography with dual detection by a photodiode array and fluorescence detectors (UPLC/DAD/FL) (Samoticha et al 2017), ultra-performance liquid chromatography with dual detection by a diode array and tandem quadrupole mass spectrometry (UPLC/ DAD/TQD) (Guerrero et al 2010a), gas chromatography-mass spectrometry (GC-MS) (Ragab et al 2006;Viñas et al 2009Viñas et al , 2011, gas chromatographymass spectrometry with selected ion monitoring (GC-MS SIM) (Rimando and Cody 2005), gas-liquid chromatography with flame ionization detection (GLC-FID) (Moriartry et al 2001), capillary electrophoresis (CE) (Ehala et al 2005) and high-speed counter-current chromatography (HSCC) (He et al 2009b). Various methods are used for analyses of stilbenes contents in the edible berries are different which could also contribute to the observed variability in the published results.…”

Section: Isolation and Identification Of Stilbenes In Edible Berriesmentioning

confidence: 99%

“…Typically, this purification utilizes an additional extraction with other solvent, often EtOAc (He et al 2009a, b;Sun et al 2006;Jiang et al 2012), silica gel (Jiang et al 2012) or C18 solid-phase extraction (Kiselev et al 2017).…”

Section: Isolation and Identification Of Stilbenes In Edible Berriesmentioning

confidence: 99%

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The stilbene profile in edible berries

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Edible berries are becoming increasingly popular to consume in fresh, dried, frozen or processed forms due to their high content and wide diversity of bioactive compounds with considerable health benefits. Among the wide variety of phytochemicals found in berries are stilbenes, which demonstrate a broad range of biological and pharmacological activities. Their content depends on many factors, including the cultivar, ripening stage, climatic conditions, agronomic management, storage conditions and postharvest management. However, the application of various abiotic and biotic external stimuli could be a strategy for increasing the production of stilbenes in edible berries. To date, several different elicitors, as inducers of plant secondary metabolite stilbenes, have been applied in different studies. This review focuses on the isolation and identification of stilbenes from edible berries and presents the influence of different external stimuli on their profile in grapes.

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The ORCID identification number(s) for the author(s) of this article can be found under https://doi.org/10.1002/admt.201900742.3D printing is on track to move into a truly transformative technology from design through operation. Additive manufacturing allows 3D items to be fabricated in a "bottom-up" fashion without subtraction (e.g., cutting and shearing) and formation (e.g., assembling and molding), leading to one-step production, maximum material utilization, and minimum expense, in stark contrast to traditional methods. Direct printing by computeraided design [1,2] boosts mass customization and lessens operation errors; even a layman can formulate any desired products free from geometrical constraints, constitutional restraints, and skill limitations. Inspired by the idea of online-distributed blueprints and localized production, the public can download digital prototypes from the cloud, modify models to fit their needs, and construct real devices anywhere, promising a world where

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Stilbenes: Quantitative extraction from grape skins, contribution of grape solids to wine and variation during wine maturation

Cited by 160 publications

References 21 publications

Biciclogermacreno, resveratrol e atividade antifúngica em extratos de folhas de Cissus verticillata (L.) Nicolson & Jarvis (Vitaceae)

Biciclogermacreno, resveratrol e atividade antifúngica em extratos de folhas de Cissus verticillata (L.) Nicolson & Jarvis (Vitaceae)

The stilbene profile in edible berries

3D Printed Random Lasers

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