Sterilizing Insects with Ionizing Radiation

Bakri, Abdeljelil; Mehta, K.; Lance, D. R.

doi:10.1007/1-4020-4051-2_9

Cited by 169 publications

(172 citation statements)

References 68 publications

Supporting

Mentioning

147

Contrasting

Unclassified

Order By: Relevance

“…Commonly, the radiation source that used on sterilization process on the SIT is radioisotopes (gamma-rays), electron beam and Xrays. Currently, the radioisotopes Co-60 and Cs-137 have been used as the gamma-rays source because these isotopes have long half-live and the energy is relatively high ( Table 2) [43].…”

Section: Sterile Insect Technique As a Prospective Methods Sterile Insmentioning

confidence: 99%

See 1 more Smart Citation

An Initiative the Used of Sterile Insect Technique (SIT) To Control Filariasis in Indonesia

Ernawan

Sasmita

2017

J. Ilmiah Aplikasi Isotop dan Radiasi

View full text Add to dashboard Cite

Filariasis as part of the neglected tropical disease is one of the health problems in the world. Filariasis divided into onchocerciasis (river blindness) and lymphatic filariasis or elephantiasis. This disease caused by filarial nematode parasites Onchocerca volvulus, Wuchereria bancrofti, Brugia malayi and Brugia timori. Filariasis transmitted by several mosquito genera as the vector. Indonesia as endemic filariasis, agreed on plays a role on World Health Organization (WHO) global filariasis elimination in 2020. Sterile insect technique (SIT) is a potential method which can be applied to filariasis elimination program by controlling the mosquito population. Basic principles of SIT involve mass rearing of species target, sterilization process using gamma-rays and releasing sterile male insect into a target area. SIT combined with other methods under one management as Area-wide Integrated Pest Management (AW-IPM) to increasing effectiveness and successful filariasis elimination program in Indonesia. Filariasis elimination program in Indonesia has several challenges and needed public participation to achieve program goals. Key words : filariasis, Indonesia, sterile insect technique (SIT) ABSTRAKFilariasis sebagai bagian dari penyakit tropis yang terbengkalai merupakan salah satu masalah kesehatan di dunia. Filariasis dibagi menjadi onchocerciasis dan filariasis limfatik atau kaki gajah. Penyakit ini disebabkan oleh parasit nematoda filarial Onchocerca volvulus, Wuchereria bancrofti, Brugia malayi dan Brugia timori. Filariasis ditularkan oleh beberapa genera nyamuk sebagai vektor. Indonesia sebagai endemik filariasis, sepakat memainkan peran dalam eliminasi filariasis global yang diagendakan oleh world health organization (WHO) pada tahun 2020. Teknik serangga mandul (TSM) adalah metode potensial yang dapat diterapkan pada program eliminasi filariasis dengan mengendalikan populasi nyamuk. Prinsip dasar SIT melibatkan pembiakan populasi target secara massal, proses sterilisasi menggunakan sinar gamma dan melepaskan serangga jantan steril ke daerah sasaran. TSM dapat dikombinasikan dengan metode lain di bawah satu manajemen terpadu, yaitu area-wide integrated pest management (AW-IPM) untuk meningkatkan efektivitas dan keberhasilan program eliminasi filariasis di Indonesia. Program eliminasi filariasis di Indonesia memiliki beberapa tantangan dan kebutuhan partisipasi masyarakat untuk mencapai tujuan program.

show abstract

Section: Sterile Insect Technique As a Prospective Methods Sterile Insmentioning

confidence: 99%

“…ambient atmosphere, doserate irradiation, temperature, cell stage and characteristics, developmental stage and age, sex, size and weight, diapauses, nutritional state have significant influences in sterilization process and need to be optimized [43][44][45][46].…”

Section: Sterile Insect Technique As a Prospective Methods Sterile Insmentioning

confidence: 99%

An Initiative the Used of Sterile Insect Technique (SIT) To Control Filariasis in Indonesia

Ernawan

Sasmita

2017

J. Ilmiah Aplikasi Isotop dan Radiasi

View full text Add to dashboard Cite

show abstract

“…Following properties of radiations are taken into consideration while selecting it for sterilization process (Bakhri et al, 2005).…”

Section: Sterilization By Ionic Radiationmentioning

confidence: 99%

“…Two types of gamma irradiators are used such as self-contained dry storage irradiators and large scale panoramic irradiators (Bakhri et al, (2005) …”

Section: Gamma Irradiatorsmentioning

confidence: 99%

Area Wide Pest Management: Concept and Approaches

Dalal¹,

Rathee²,

Singh³

2017

Int.J.Curr.Microbiol.App.Sci

View full text Add to dashboard Cite

“…The maturation of the cell into a gamete or the participation of the gamete to form the zygote are not affected by the dominant lethal mutation happening in a germ cell but causes the death of the developing embryo [28]. The earlier stages of spermatogenesis (spermatocytes and spermatogonia) are more radiosensitive than later stages (spermatids and spermatozoa) in terms of irreversible damage and this can result in the death of the developing cell [29,30]. Irradiation of the later stages results in dominant lethal mutations in spermatozoa that lead to embryonic mortality after fertilization [30][31][32].…”

Section: Effects Of Irradiationmentioning

confidence: 99%

The development of new radiation protocols for insect sterilization using long wavelength x-rays

Urquidi

Brar

Rodriguez

et al. 2015

AIP Conference Proceedings

View full text Add to dashboard Cite

Abstract. Control of insect species for the protection of crops, livestock, and prevention of disease such as dengue fever and malaria is a high priority in today's global economy. Traditional methods such as pesticides have fallen out of favor because its effects are indiscriminate as well as adverse and unpredictable impacts on the environment. Modern novel techniques such as genetic modification have had trouble gaining traction due to ethics concerns and the potential for unforeseen side effects. One approach that has gained traction and has proven its efficacy is the use of ionizing radiation to affect sterility in insect species in order to scale back their population. Known as Sterile Insect Technique (SIT), it has proven very effective in eradicating certain dipteran insect populations. However, when standard sterilization methods developed for dipertans are applied to mosquito populations significant complications arise, such as an inability to compete with non-irradiated males and high mortality rates. We have investigated the effect of treatment with x-rays of different wavelengths on x-ray sterilized mosquito males. Our results have demonstrated that longer wavelength x-rays have a significant effect on the outcome of the sterile males' longevity as well as an increase on the efficacy of sterilization while employing a substantially lower dose. OVERVIEWWe have investigated the utilization of X-ray radiation to achieve sterilization for use in insect pest management programs. The denials of trans-boundary shipments of radioisotopes due to political instabilities are creating a severe constraint to sterile insect technique (SIT) programs around the world as SIT relies on the use of ionizing radiation from radioisotopes for insect sterilization. In SIT programs a large number of sterilized males are released area-wide. The sterile males compete with wild males for female insects. If a female mates with a sterile male then it will have no offspring. Ultimately, this leads to a reduction of the wild population [1]. The sexual sterility is induced with gamma radiation emitted from radioisotopes such as Cesium-137 and Cobalt-60 in almost all SIT programs. The Gammacell 220, a 60 Co irradiator (MDS Nordion International Inc., Ottawa, ON, Canada) has been the most commonly used irradiator and has proven extremely reliable for the purpose of sterilizing target insect pests. This technique has been used successfully for suppression, eradication, containment and prevention of many insect pests [2,3]. The use of sterile insects in area-wide integrated pest management (AW-IPM) programs will continue to expand as constraints are increasing on the use of chemical pesticides in relation to the public's growing demand for a cleaner environment and residue-free food.In 2006, a serious problem arose when the production of the Gammacell 220 irradiator was discontinued. The future availability of these small scale irradiators is in doubt due to growing difficulties associated with the transboundary shipment of radioisotop...

show abstract

Sterilizing Insects with Ionizing Radiation

Cited by 169 publications

References 68 publications

An Initiative the Used of Sterile Insect Technique (SIT) To Control Filariasis in Indonesia

An Initiative the Used of Sterile Insect Technique (SIT) To Control Filariasis in Indonesia

Area Wide Pest Management: Concept and Approaches

The development of new radiation protocols for insect sterilization using long wavelength x-rays

Contact Info

Product

Resources

About