Stereoselective Construction of 3a‐Methylhydrindans Starting from 2,7‐Enynol Derivatives Based on Ti(II)‐Mediated Cyclization and Ru‐Catalyzed Ring‐Closing Metathesis.

Abstract

Stereoselective Construction of 3a-Methylhydrindans Starting from 2,7-Enynol Derivatives Based on Ti(II)-Mediated Cyclization and Ru-Catalyzed Ring-Closing Metathesis. -The efficient two-step method developed for the diastereoselective construction of tetrahydroindenes can also be applied to other ring systems. -(OHKUBO, M.; UCHIKAWA, W.; MATSUSHITA, H.; NAKANO, A.; SHIRATO, T.; OKAMOTO*, S.; Tetrahedron Lett. 47 (2006) 29, 5181-5185; Dep. Appl. Chem., Fac. Eng., Kanagawa Univ., Kanagawa, Yokohama 221, Japan; Eng.) -Mais 44-106