2017
DOI: 10.1590/0102-6720201700020007
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Stem Cells Hematopoietic Niches and Inflammatory Response to Different Synthetic Prosthesis Implanted in Rat With Incisional Hernias

Abstract: Background: Extramedullary hematopoiesis depends on complex pathophysiological mechanisms linked to hematopoietic stem cells and the proteins considered mediators of the inflammation. The identification of hematopoietic cells outside bone marrow in the adult is an occurrence that can occasionally follows the inflammatory response, was considered a secondary occurrence, but current biomolecular studies have changed that concept. Aim: Describe the presence of clusters of precursor cells of platelets (megakaryo… Show more

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Cited by 3 publications
(3 citation statements)
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“…Giant cells (clusters of macrophages) are a common finding in chronic inflammation, triggered by the presence of agents with low immune activity, such as non-absorbable materials 28 .The water control group and the propolis group differed significantly with regard to the number of giant cells (p≤ 0.001), suggesting red propolis has anti-inflammatory activity.…”
Section: Angiogenesismentioning
confidence: 99%
“…Giant cells (clusters of macrophages) are a common finding in chronic inflammation, triggered by the presence of agents with low immune activity, such as non-absorbable materials 28 .The water control group and the propolis group differed significantly with regard to the number of giant cells (p≤ 0.001), suggesting red propolis has anti-inflammatory activity.…”
Section: Angiogenesismentioning
confidence: 99%
“…Polypropylene is a synthetic material that produces little tissue reaction and good tensile strength, which strength lasts for several years after its use in living organisms. However, even with this possible choice, the use of meshes still has several side effects 4 , such as increased postoperative pain, abdominal adhesions and areas of fibrosis and increased risk of infection due to the placement of the prosthesis 18 .…”
Section: Introductionmentioning
confidence: 99%
“…Post-operative pain, recurrence, expensive technique, type of anesthesia and time to return to work are among the topics discussed. Wasing time in the surgery of external hernia is associated with extended hospitalazation and a prolonged intensive care, hence resulting in unexpected health costs, in addition to altered mortality and morbidity 4,5 .…”
Section: Introductionmentioning
confidence: 99%