2012
DOI: 10.1007/s10616-012-9489-3 View full text |Buy / Rent full text
|
|

Abstract: Human umbilical cord mesenchymal stem cells (hUMSC) are primitive multipotent cells capable of differentiating into cells of different lineages. They can be an alternative source of pluripotent cells since they are ethically and regulatory approved, are easily obtained and have low immunogenicity compared to embryonic stem cells which are dogged with numerous controversies. hUMSC can be a great source for cell and transplantation therapy.

Help me understand this report

Search citation statements

Order By: Relevance
Select...
2
2
0
5
0

Year Published

2015
2015
2020
2020

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

0
5
0
Order By: Relevance
“…Thus the purpose of this study was to evaluate the osteogenic response of the cells to miR‐21. Human umbilical cord mesenchymal stem cells (hUMSCs) can be isolated and stored easily, and differentiate faster than bone marrow mesenchymal stem cells (BMSCs), so hUMSCs were choosen as a model in this study . The miR‐21‐mediated pathway PTEN‐AKT‐β‐catenin was also explored.…”
mentioning
Create an account to read the remaining citation statements from this report. You will also get access to:
  • Search over 1.2b+ citation statments to see what is being said about any topic in the research literature
  • Advanced Search to find publications that support or contrast your research
  • Citation reports and visualizations to easily see what publications are saying about each other
  • Browser extension to see Smart Citations wherever you read research
  • Dashboards to evaluate and keep track of groups of publications
  • Alerts to stay on top of citations as they happen
  • Automated reference checks to make sure you are citing reliable research in your manuscripts
  • 7 day free preview of our premium features.

Trusted by researchers and organizations around the world

Over 130,000 students researchers, and industry experts at use scite

See what students are saying

rupbmjkragerfmgwileyiopcupepmcmbcthiemesagefrontiersapsiucrarxivemeralduhksmucshluniversity-of-gavle
“…Thus the purpose of this study was to evaluate the osteogenic response of the cells to miR‐21. Human umbilical cord mesenchymal stem cells (hUMSCs) can be isolated and stored easily, and differentiate faster than bone marrow mesenchymal stem cells (BMSCs), so hUMSCs were choosen as a model in this study . The miR‐21‐mediated pathway PTEN‐AKT‐β‐catenin was also explored.…”
mentioning
“…The multipotency of HUCPVCs and their ability to differentiate to two testicular cell lineages under the same culture conditions can likely be attributed to their inherent heterogeneity. Others have identified a subpopulation of very small embryonic-like cells (VSELs) expressing OCT4A and SSEAA [ 57 , 58 ] from umbilical cord [ 59 , 60 ] and other tissues [ 57 , 58 ]. We previously showed that a subpopulation of HUCPVCs express OCT4A and SSEA4 [ 22 ], but it remains to be determined whether these cells correspond to previously characterized pluripotent VSELs.…”
Section: Discussionmentioning
“…In short, WJMSCs are uniquely immune-privileged; they are not rejected by an allogenic host and thus their allogenic transplantation is associated with no need for immunosuppression [ 5 , 30 , 35 ]. In addition, WJMSCs can be safely expanded to “as needed” quantities [ 5 , 7 , 10 ], can be phenotypically selected on a large scale to create repositories of distinct WJMSC populations [ 36 ], and – if needed – can be further reprogrammed/engineered towards the desired cell lines [ 10 , 13 , 37 ]. Moreover, evidence is accumulating for WJMSCs’ successful use in engineering biological cardiac tissues [ 38 40 ] and an allogenic non-rejectable bioartificial heart [ 41 ].…”
Section: Discussionmentioning