Steatocystoma multiplex. A facial papular variant

Nishimura, M.

doi:10.1001/archderm.122.2.205

Cited by 13 publications

(12 citation statements)

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“…Cases of SM with milium-like cysts have rarely been reported in the literature [18, 19]. In addition, the term ‘facial papular variant’ of SM has been proposed to describe a peculiar type of SM with papular lesions less than 5 mm in diameter exclusively located on the face and on the scalp [20, 21]. Finally, in 1994 Menni and Piccinno [22] described 2 infants with persistent infantile milia and the father of one of them had presented typical SM since puberty.…”

Section: Discussionmentioning

confidence: 99%

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

et al. 1998

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Background: Steatocystoma multiplex (SM) and eruptive vellus hair cysts (EVHC) are conditions characterized by numerous cutaneous cysts with a clinical resemblance, such as age of onset, location, appearance of the lesions and mode of inheritance, but with distinctive histologic features. Recently, some authors have proposed that the two conditions are variants of one entity originating in the pilosebaceous duct, while others suggest that SM and EVHC are two distinct entities, on the basis of the different expression of keratins. Milia are small round cysts, commonly involving the face. In 1994, Menni and Piccinno reported the first association, in a family, between persistent infantile milia in a 9-month-old girl and SM in the father. The authors hypothesized a relationship between these two conditions. Objective: We describe a family in which the mother showed cystic lesions and milia and her 4-year-old son and her 18-month-old daughter presented persistant infantile milia. Methods: In addition to the clinical and genetic documentation, a biopsy was performed in the son and two biopsies in the mother. Results: The histologic examination of one of the son’s milium-like papules showed in the superficial dermis a small cyst typical of a milium. In serial sections it was possible to see a connection with a vellus hair follicle by an epithelial pedicle. The histologic examination of one of the mother’s papules on the forehead showed a large round cystic structure with histologic features of EVHC. Close to the cyst wall, serial sections showed flattened sebaceous gland lobules. The histologic findings of the second biopsy taken from the chest showed the typical features of a steatocystoma. Conclusions: The relationship between milia, SM and EVHC is discussed; the three diseases should be considered as subtypes of multiple pilosebaceous cysts that may all present overlapping histologic features. The different level of the pilosebaceous duct where the cyst originates should explain the different clinical manifestations.

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Section: Discussionmentioning

confidence: 99%

Persistent Milia, Steatocystoma multiplex and Eruptive Vellus Hair Cysts: Variable Expression of Multiple Pilosebaceous Cysts within an Affected Family

et al. 1998

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“…Multiple lesions engender psychologic effects which are usually seen with the facial papular variant. 37,38 Steatocystomas classically arise in children and adolescents but can be seen in any age group. 39 This entity shares a close histologic relationship with eruptive vellus hair cysts.…”

Section: Steatocystomamentioning

confidence: 99%

Cutaneous Neoplasms with Sebaceous Differentiation

Schlauder

Morgan

2007

Pathology Case Reviews

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Cutaneous adexal tumors of sebaceous origin are a diverse group of neoplasms which require special consideration both histologically and clinically. Often the skin is the only visible manifestation of many underlying conditions. Therefore, it is paramount that theses neoplasms be correctly identified and thoroughly understood. This paper serves as a comprehensive review of sebaceous tumors and emphasizes their key clinical and histological characteristics.

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“…The lesions typically appear in childhood or early adulthood, but in some patients the lesions have developed late in life 3,4 . The cysts are located principally on the axillae, groin, trunk, scrotum and proximal extremities and they are rarely localized to the face and scalp [3][4][5][6] . Steatocystoma multiplex located on the face and scalp has been divided into three types [3][4][5][6] : 1) a facial papular variant type 5 , 2) sebocystomatosis6 and 3) cysts located exclusively on the scalp 3,4 .…”

Section: Introductionmentioning

confidence: 99%