Stationary chest tomosynthesis using a CNT x-ray source array

Shan, Jing; Chtcheprov, Pavel; Tucker, Andrew; Lee, Yueh Z.; Wang, Xiaohui; Foos, David H.; Heath, Michael D.; Lu, Jianping; Zhou, Otto

doi:10.1117/12.2007993

Cited by 16 publications

(19 citation statements)

References 12 publications

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“…A simple linear multiple source using an array of 31 CNT FE cathodes has also been constructed, for the purposes to digital breast tomosynthesis, which was shown to be capable of a total scan angle of 30° [171]. In a further extension, a digital chest tomosynthesis scanner was demonstrated [238]. This system used 75 CNT FE sources, operating at up to 80 kV with a 20°beam angle.…”

Section: Static Tomography and Tomosynthesismentioning

confidence: 98%

X-ray generation using carbon nanotubes

et al. 2015

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Since the discovery of X-rays over a century ago the techniques applied to the engineering of X-ray sources have remained relatively unchanged. From the inception of thermionic electron sources, which, due to simplicity of fabrication, remain central to almost all X-ray applications, there have been few fundamental technological advances. However, with the emergence of ever more demanding medical and inspection techniques, including computed tomography and tomosynthesis, security inspection, high throughput manufacturing and radiotherapy, has resulted in a considerable level of interest in the development of new fabrication methods. The use of conventional thermionic sources is limited by their slow temporal response and large physical size. In response, field electron emission has emerged as a promising alternative means of deriving a highly controllable electron beam of a well-defined distribution. When coupled to the burgeoning field of nanomaterials, and in particular, carbon nanotubes, such systems present a unique technological opportunity. This review provides a summary of the current state-of-the-art in carbon nanotube-based field emission X-ray sources. We detail the various fabrication techniques and functional advantages associated with their use, including the ability to produce ever smaller electron beam assembles, shaped cathodes, enhanced temporal stability and emergent fast-switching pulsed sources. We conclude with an overview of some of the commercial progress made towards the realisation of an innovative and disruptive technology.

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Section: Static Tomography and Tomosynthesismentioning

confidence: 98%

X-ray generation using carbon nanotubes

et al. 2015

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“…19,22 The modulation transfer function (MTF) is 1.7cycles/min in the scanning direction and 3.4 cycles/min in the perpendicular direction. 19 The anode is made of tungsten and there is 2.8mm of aluminum for filtration. The anode voltage is set by using a Spellman High Voltage Power Supply (model XRV160P1800).…”

Section: S-dct Systemmentioning

confidence: 99%

“…[15][16][17] Using the x-ray source array, the stationary digital chest tomosynthesis (s-DCT) system can achieve full angular coverage in tomosynthesis imaging with no moving parts. 14,[18][19][20] Previous studies on the stability and geometry of the s-DCT system have been published. 21,19,22,23 The purpose of this study was to evaluate the feasibility of using the prototype s-DCT device for patient imaging.…”

Section: Introductionmentioning

confidence: 99%

“…14,[18][19][20] Previous studies on the stability and geometry of the s-DCT system have been published. 21,19,22,23 The purpose of this study was to evaluate the feasibility of using the prototype s-DCT device for patient imaging. Additionally, we gauged radiologists' confidence levels in evaluating patient disease levels in the Cystic Fibrosis (CF) population.…”

Section: Introductionmentioning

confidence: 99%

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Initial clinical evaluation of stationary digital chest tomosynthesis

Hartman¹,

Shan²,

Wu³

et al. 2016

SPIE Proceedings

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Computed Tomography (CT) is the gold standard for image evaluation of lung disease, including lung cancer and cystic fibrosis. It provides detailed information of the lung anatomy and lesions, but at a relatively high cost and high dose of radiation. Chest radiography is a low dose imaging modality but it has low sensitivity. Digital chest tomosynthesis (DCT) is an imaging modality that produces 3D images by collecting x-ray projection images over a limited angle. DCT is less expensive than CT and requires about 1/10 th the dose of radiation. Commercial DCT systems acquire the projection images by mechanically scanning an x-ray tube. The movement of the tube head limits acquisition speed.We recently demonstrated the feasibility of stationary digital chest tomosynthesis (s-DCT) using a carbon nanotube (CNT) x-ray source array in benchtop phantom studies. The stationary x-ray source allows for fast image acquisition. The objective of this study is to demonstrate the feasibility of s-DCT for patient imaging. We have successfully imaged 31 patients. Preliminary evaluation by board certified radiologists suggests good depiction of thoracic anatomy and pathology.

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“…Multiple individually controllable X-ray sources are spatially distributed in a single X-ray tube to eliminate the need to position the X-ray source at different locations during image acquisition. This technology enables stationary tomography, which has been demonstrated in digital breast tomosynthesis, 32-34 digital chest tomosynthesis, 35,36 tomosynthesis-guided radiation therapy 37 and stationary CT for homeland security. 38 The purpose of this study was to investigate the feasibility of using a CNT X-ray source array for stationary intraoral tomosynthesis (s-IOT).…”

Section: Introductionmentioning

confidence: 99%

Stationary intraoral digital tomosynthesis using a carbon nanotube X-ray source array

Shan¹,

Tucker²,

Gaalaas³

et al. 2015

Dentomaxillofacial Radiology

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Objectives: Intraoral dental tomosynthesis and closely related tuned-aperture CT (TACT) are low-dose three-dimensional (3D) imaging modalities that have shown improved detection of multiple dental diseases. Clinical interest in implementing these technologies waned owing to their time-consuming nature. Recently developed carbon nanotube (CNT) X-ray sources allow rapid multi-image acquisition without mechanical motion, making tomosynthesis a clinically viable technique. The objective of this investigation was to evaluate the feasibility of and produce high-quality images from a digital tomosynthesis system employing CNT X-ray technology. Methods: A test-bed stationary intraoral tomosynthesis unit was constructed using a CNT X-ray source array and a digital intraoral sensor. The source-to-image distance was modified to make the system comparable in image resolution to current two-dimensional intraoral radiography imaging systems. Anthropomorphic phantoms containing teeth with simulated and real caries lesions were imaged using a dose comparable to D-speed film dose with a rectangular collimation. Images were reconstructed and analysed. Results: Tomosynthesis images of the phantom and teeth specimen demonstrated perceived image quality equivalent or superior to standard digital images with the added benefit of 3D information. The ability to "scroll" through slices in a buccal-lingual direction significantly improved visualization of anatomical details. In addition, the subjective visibility of dental caries was increased. Conclusions: Feasibility of the stationary intraoral tomosynthesis is demonstrated. The results show clinical promise and suitability for more robust observer and clinical studies.

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Stationary chest tomosynthesis using a CNT x-ray source array

Cited by 16 publications

References 12 publications

X-ray generation using carbon nanotubes

X-ray generation using carbon nanotubes

Initial clinical evaluation of stationary digital chest tomosynthesis

Stationary intraoral digital tomosynthesis using a carbon nanotube X-ray source array

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