1974
DOI: 10.1001/archderm.109.2.239
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Staphylococcal scalded skin syndrome. Adult onset in a patient with deficient cell-mediated immunity

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Cited by 12 publications
(4 citation statements)
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“…The increased mortality of SSSS in adult patients suggested by our study agrees with much of the literature 2,3,6 . This increased mortality is likely partially attributable to the fact that adult patients with SSSS are more likely to be immunocompromised, and thus are unable to clear infections before progression, and have chronic comorbidities including renal impairment, which hampers the ability to remove bacterial toxins 3,7,8 . Our study corroborates the literature while adding more information to the baseline differences between older and younger patients.…”
Section: Unadjusted Odds P‐value Adjusted Odds P‐valuesupporting
confidence: 88%
“…The increased mortality of SSSS in adult patients suggested by our study agrees with much of the literature 2,3,6 . This increased mortality is likely partially attributable to the fact that adult patients with SSSS are more likely to be immunocompromised, and thus are unable to clear infections before progression, and have chronic comorbidities including renal impairment, which hampers the ability to remove bacterial toxins 3,7,8 . Our study corroborates the literature while adding more information to the baseline differences between older and younger patients.…”
Section: Unadjusted Odds P‐value Adjusted Odds P‐valuesupporting
confidence: 88%
“…These included immunosuppression, diabetes, presence of neoplastic disease, and possible immunological immaturity. Other workers described cases of staphylococcal scalded-skin syndrome in compromised adults (10,11,16,19). The relatively low incidence of this syndrome may be due to failure to recognize it in its protean manifestations or to a 520 WILEY, GLASGOW, AND ROGOLSKY requirement that depressed host defenses be present to allow initiation of infection in most adults.…”
Section: Discussionmentioning
confidence: 99%
“…aureus from blood cultures (Table ) . In addition, as opposed to paediatric patients who are usually in otherwise good health when they develop SSSS, virtually all adults with SSSS were immunocompromised, with chronic renal disease, HIV infection, graft‐versus‐host disease, malignant neoplasms, chemotherapy, intravenous drug abuse or diabetes mellitus . Similar to paediatric patients, adults with SSSS demonstrate a fever, and oedematous erythema of the eyelids and nostrils.…”
Section: Clinical Features In Adultsmentioning
confidence: 99%