Stannous fluoride forms aggregates between outer and inner membranes leading to membrane rupture of Porphyromonas gingivalis and Prevotella pallens
Sancai Xie,
Vighter Iberi,
Ying Boissy
et al.
Abstract:ObjectiveStannous has been shown to bind to free lipopolysaccharides, thus preventing them from binding to TLR receptors. This study was undertaken to determine the histomorphological mechanism of stannous binding to anaerobic bacteria.MethodsTwo bacteria associated with gingivitis and advanced periodontal disease, Porphyromonas gingivalis (P. gingivalis) and Prevotella pallens (P. pallens), were cultured in 25–1,000 μM of stannous fluoride and stannous chloride for 48 h. The growth rate was estimated using ab… Show more
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