On March 18, the Centers for Medicare & Medicaid Services issued guidance that all nonurgent surgeries and medical procedures be delayed during the COVID-19 pandemic. This recommendation was made to conserve personal protective equipment, a critical resource in the care of patients with COVID-19. Although the necessity of this recommendation is clear, progress must continue to be made on other serious non-COVID-19 challenges in public health.Among the procedures being delayed are colonoscopies, the most commonly used test to screen for and prevent colorectal cancer. As the second highest cause of cancer deaths in the United States, colorectal cancer is largely preventable through screening. However, nearly 23 million adults aged 50 to 75 are past due for screening, and an estimated 000 Americans">53 000 Americans will die from colorectal cancer this year. To reduce colorectal cancer mortality, the National Colorectal Cancer Roundtable, a coalition established by the American Cancer Society and the Centers for Disease Control and Prevention, launched this year its "80% in Every Community" campaign, which aims to increase colorectal cancer screening rates substantially in all US communities. Since the Centers for Medicare and Medicaid Services recommendation to delay nonurgent procedures in mid-March, adult primary care and gastroenterology visits have declined by 49% and 61%, respectively, which makes achieving colorectal cancer screening goals even more challenging.Delaying colorectal cancer screening for the 23 million adults who are past due will lead to delayed diagnoses and cancer deaths. Delays in screening will widen persistent racial, ethnic, and socioeconomic mortality disparities as rising unemployment in disadvantaged populations stifles already limited access to care. Delays will also overwhelm health care systems burdened by long screening backlogs when elective procedures resume.