Staging of cervical carcinoma: Accuracy of magnetic resonance imaging and computed tomography

Janus, Cynthia; Mendelson, David S.; Moore, Sandra L.; Gendal, Ellen S.; Dottino, Peter; Brodman, Michael

doi:10.1016/0899-7071(89)90089-2

Cited by 44 publications

(14 citation statements)

References 8 publications

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“…On MR imaging, the preservation of a low-signal intact rim of cervical stroma on T2-weighted images between the hyperintense tumor and the paracervical tissue is a reliable sign of intact parametrium [4,12]. In applying these criteria, we have shown that the accuracy in the assessment of parametrial invasion by MR imaging is as high as 95 %, which is similar to the results of previous studies by Janus et al [19] and Subak et al [20]who reported an 86±94 % accuracy rate. There was no false-negative result in the present study.…”

Section: Discussionsupporting

confidence: 89%

Preoperative staging of cervical carcinoma with MR imaging: a reappraisal of diagnostic accuracy and pitfalls

et al. 2001

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The purpose of this study was to assess the diagnostic accuracy and pitfalls of MR imaging in preoperative staging of cervical cancer. Magnetic resonance imaging was performed to determine the tumor staging for 41 patients with cervical carcinoma emphasizing tumor size, parametrial invasion, vaginal invasion, and lymph node metastases. According to the correlation of MR findings with surgical-pathological features, there was less than 5 mm discrepancy in the size in 29 of 34 tumors (85.3%) that were larger than 1 cm. In assessing parametrial invasion, vaginal invasion and lymph node metastases, MR imaging had an accuracy of 95, 83, and 86%, respectively. In determining stage of disease and differentiating operable (< or =stage IIA) from advanced disease (> or =stage IIB), MR imaging had an accuracy of 82.9 and 93%. Pitfalls leading to staging errors included difficulties in differentiating cancer foci from surrounding tissue edema and detecting microscopic tumor extension. Magnetic resonance imaging is accurate in the evaluation of parametrial invasion and differentiation of operable from advanced disease. The ability of MR imaging to detect microscopic extra-cervical tumor extension and differentiate cancer foci from surrounding tissue edema is not as reliable.

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Section: Discussionsupporting

confidence: 89%

Preoperative staging of cervical carcinoma with MR imaging: a reappraisal of diagnostic accuracy and pitfalls

et al. 2001

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“…Lymph node status is the most important prognostic factor in patient evaluation and determines treatment selection. Early published results are encouraging, 32,33,70 and the GOG is planning a large validation trial involving patients with Stage IB1 disease. Of special interest is that mapping can be performed during laparoscopy, the ideal combination of two minimally invasive surgical concepts.…”

Section: Lymphatic Mappingmentioning

confidence: 99%

Imaging in cervical cancer

Follen

Levenback

Iyer

et al. 2003

Cancer

126

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“…[13] 1988 P Pelvic and para-aortic ----3 1 9 38 ----Chu [14] 1996 P Pelvic ----4 1 6 17 ----Grumbine [15] 1981 P Pelvic and para-aortic ----0 1 6 17 ----Heller [16] 1990 [20] 1989 P Pelvic and para-aortic ----5 2 2 61 ----Subak [21] 1995 P Pelvic ----3 3 2 29 8 5 5 53 Engelshoven [22] 1984 P Para-aortic ----3 4 1 12 ----Walsh [23] 1981 P Para-aortic ----11 2 2 0 ----Yang [24] 2000 R Pelvic ----11 2 6 57 12 6 5 53 Choi [25] 2004 R Pelvic --------8 14 6 198 Chung [26] 2007 P Pelvic and para-aortic --------24 10 6 59 Chung [26] 2007 R Pelvic and para-aortic --------30 44 66 693 Greco [27] 1989 P Pelvic and para-aortic --------3 6 5 32 Hawighorst [28] 1998 P Pelvic --------13 3 6 11 Hawnaur [29] 1994 P Pelvic and para-aortic --------12 4 4 29 Hricak [30] 1988 P Pelvic and para-aortic --------9 2 2 44 Janus [31] 1989 P Para-aortic [35] 2007 P Pelvic and para-aortic --------7 11 12 120 Sahdev [35] 2007 N Pelvic and para-aortic --------12 15 [55] 1980 P Pelvic and para-aortic ----12 3 3 7 ----Brenner [56] 1982 P Para-aortic ----4 0 2 6 ----Brenner [56] 1982 P Pelvic ----4 1 2 13 ----Villasanta [57] 1983 P Para-aortic ----10 4 3 25 ----Wenzel [58] 1985 P Para-aortic ----10 1 2 20 ----Wenzel [58] 1985 …”

Section: Disclosure Statementmentioning

confidence: 99%

A Comprehensive Comparison of CT, MRI, Positron Emission Tomography or Positron Emission Tomography/CT, and Diffusion Weighted Imaging-MRI for Detecting the Lymph Nodes Metastases in Patients with Cervical Cancer: A Meta-Analysis Based on 67 Studies

Liu

Gao²,

Li³

2017

Gynecol Obstet Invest

159

105

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Object: In recent times, many published papers reported the diagnostic performance of CT, MRI, positron emission tomography (PET) using 2-[¹⁸F] fluoro-2-deoxy-D-glucose (FDG) and diffusion-weighted magnetic resonance imaging (DW-MRI) for detecting the lymph nodes (LNs) metastases in patients with cervical cancer. This study is aimed at assessing and comparing the diagnostic value of those non-invasive modalities in detecting the LNs metastases in cervical cancer patients. Methods: Studies on the non-invasive modalities for the detection of metastatic LNs were searched in PubMed, Medline, Web of Science, Cochrane Library and Embase databases. Pooled positive likelihood ratios and negative likelihood ratios, diagnostic OR, area under curve (AUC), summary receiver operating characteristics were calculated as evaluation indices. Results: In region- or node-based analysis, the AUC of DWI-MRI (0.92) and PET or PET/CT (0.90) were better than CT (0.83), and the difference was significant (DWI-MRI vs. CT: Z = 4.61, p < 0.001; PET or PET/CT vs. CT: Z = 3.61, p = 0.001). Conclusion: Among the 4 non-invasive modalities, the PET or PET/CT has the highest specificity, and DWI-MRI has the highest sensitivity.

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Staging of cervical carcinoma: Accuracy of magnetic resonance imaging and computed tomography

Cited by 44 publications

References 8 publications

Preoperative staging of cervical carcinoma with MR imaging: a reappraisal of diagnostic accuracy and pitfalls

Preoperative staging of cervical carcinoma with MR imaging: a reappraisal of diagnostic accuracy and pitfalls

Imaging in cervical cancer

A Comprehensive Comparison of CT, MRI, Positron Emission Tomography or Positron Emission Tomography/CT, and Diffusion Weighted Imaging-MRI for Detecting the Lymph Nodes Metastases in Patients with Cervical Cancer: A Meta-Analysis Based on 67 Studies

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