We consider the periodic problem for two-fluid non-isentropic Euler-Maxwell systems in plasmas. By means of suitable choices of symmetrizers and an induction argument on the order of the time-space derivatives of solutions in energy estimates, the global smooth solution with small amplitude is established near a non-constant equilibrium solution with asymptotic stability properties. This improves the results obtained in [15] for models with temperature diffusion terms by using the pressure functions p ν in place of the unknown variables densities n ν . 2000 Mathematics Subject Classification: 35L45, 35L60, 35L65, 35Q60, 76X05 Keywords: Two-fluid non-isentropic Euler-Maxwell systems, plasmas, non-constant equilibrium solutions, global smooth solutions, long time behavior. Remark 1.2 The result in Theorem 1.1 for two-fluid non-isentropic Euler-Maxwell systems still holds for two-fluid non-isentropic Euler-Poisson systems which can be regarded as a special case of the former systems by setting B = 0 and E = −∇Ψ (see [7, 25]) . Remark 1.3 Different from the proof process in [15], we choose a new symmetrizer like (2.25)here. The effect of temperature diffusion in non-isentropic Euler-Maxwell equations has been released successfully by this suitable choices of symmetrizers and the techniques of using the pressure functions p ν in place of the unknown variables densities n ν (see [16,18]).Remark 1.4 It should be emphasized that the velocity relaxation and temperature terms of the considered two-fluid non-isentropic Euler-Maxwell system here play a key role in the proof of Theorem 1.1. We shall study in the other forthcoming work the case of non-relaxation for which the proof is much more complicated to carry out.