Stability of high-performance liquid chromatography columns packed with poly(methyloctylsiloxane) sorbed and radiation-immobilized onto porous silica and zirconized silica

Immobilized polymeric stationary phases using metalized silica supports

“…The metalized (zirconized or titanized) silica materials were prepared by simple procedures using a low reaction temperature [18,[36][37][38] or, in some cases, reactions with reflux in an argon atmosphere [17,[33][34][35]. The zirconium and titanium amounts incorporated onto the silica particles depended on the type of procedure used.…”

“…The majority of the stationary phases were prepared by deposition of PMOS into the pores of zirconized [33,34] and titanized [17,35] silica particles. Initially a 10 lm silica was used and the PMOS was immobilized by gamma radiation using doses of 80 or 120 kGy.…”

“…Recently, LabCrom has produced some stationary phases with polymers (polybutadiene and polysiloxanes) immobilized onto silica particles coated with more stable oxide layers (zirconia or titania) [17,19,[33][34][35][36], the socalled metalized silica supports. These supports incorporate the ideal chromatographic characteristics of silica to the stability of the alternative oxides [37,38].…”

“…These supports incorporate the ideal chromatographic characteristics of silica to the stability of the alternative oxides [37,38]. Some early studies have shown that these new stationary phases present higher stability and have chromatographic performance similar to the stationary phases based on polymers immobilized onto bare silica particles [17,34].…”

Preparação, caracterização e aplicação de fases estacionárias tipo C8 modificadas por óxidos metálicos para cromatografia líquida

“…19,20 A imobilização térmica do PMOS sobre a sílica aluminizada foi feita de acordo com o método empregado por Bottoli, 21 onde a sílica aluminizada com PMOS foi colocada dentro de um reservatório de aço inox e submetido à uma temperatura de 120 ºC por 16 h na presença de ar.…”