Eur. J. Chem. volume 5, issue 2, P311-320 2014 DOI: 10.5155/eurjchem.5.2.311-320.951
Lobna Abd El Aziz Hussien, Maha Farouk Abdel Ghani, Amal Mahmoud Abo El-Alamein, Ekram Hany Mohamed
Abstract:

KEYWORDSSimple, sensitive and precise spectrophotometric and chemometric stability indicating techniques were adopted for Olanzapine (OLA) determination in presence of its degradation products over a concentration range of 0.002-0.02 mg/mL. The spectrophotometric technique involves six methods; first method is first derivative (D1) spectrophotometric one, which allows the determination of OLA in presence of its acidic and alkaline degradation products at 261.2 and 260.6 nm with mean percentage recoveries …

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