Squamous cell carcinoma of the renal pelvis: nephrostomy tract tumour seeding

Corvino, C.; Meliani, E.; Masieri, Lorenzo; Lapini, A.; Serni, Sergio; Carini, Marco

doi:10.1111/j.1464-410x.2003.02947.x

Cited by 3 publications

(4 citation statements)

References 2 publications

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“…17 On closer review of fourteen case reports of "tract seeding" for UTUC from 1986 to 2017, only 2 cases resulted following true PCNB, while 12 occurred following percutaneous resection or placement of a nephrostomy tube. 12,[18][19][20][21][22][23][24][25][26][27][28][29][30] Utilization of coaxial technique in the 2 historical cases of PCNB were 18,19 Our interpretation of these results in light collective work is that PCNB appears to be safe, especially when using contemporary coaxial technique, while percutaneous resection or nephrostomy tube placement may carry a higher rate of tract seeding. The mechanism of tract seeding in cases of percutaneous resection or nephrostomy tube placement is likely secondary to significant reflux of malignant cells along the percutaneous tract, which would theoretically be minimized by PCNB, particularly in the setting of coaxial technique.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous Image-guided Core Needle Biopsy for Upper Tract Urothelial Carcinoma

Joseph

Potretzke

Packiam

et al. 2020

Urology

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Section: Discussionmentioning

confidence: 99%

Percutaneous Image-guided Core Needle Biopsy for Upper Tract Urothelial Carcinoma

Joseph

Potretzke

Packiam

et al. 2020

Urology

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“…This site metastasis has a very low incidence and a small number of cases has been reported in literature ( table 1 ) [4][5][6][7][8][9] . One of the first reports by Sharma et al [5] described a percutaneous nephroscopic resection of TCC involving the renal pelvis.…”

Section: Discussionmentioning

confidence: 99%

“…All case reports showed aggressive high-grade tumors [4][5][6][7][8][9] . The spreading along the percutaneous access route could be avoided by a retrograde endoscopic approach [5] .…”

Section: Discussionmentioning

confidence: 99%

“…Seven months later, he was admitted for left flank pain due to a mass along the percutaneous track site. Mass en-bloc resection was performed, and histopathology finding demonstrated undifferentiated carcinoma, The UC tumor recurrence has been frequently investigated in high-grade and high-stage disease, while the spilling of tumor cells along nephrostomy tract is an issue rarely reported in the literature [4][5][6][7][8][9] . …”

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confidence: 99%

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Upper Urinary Tract Urothelial Carcinoma Tumor Seeding along Percutaneous Nephrostomy Track: Case Report and Review of the Literature

et al. 2016

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Upper urinary tract urothelial carcinomas (UTUC) account for 5-10% of all transitional cells neoplasms. Kidney-sparing treatment should be considered for low grade (LG) UTUC and for imperative conditions. Percutaneous approach may have a role in LG tumors not manageable endoscopically. Tumor seeding along nephrostomy track is a rare report. We describe the case of a 73-year-old male, with a history of high-grade UC of the left renal pelvis. A CT scan showed the thickening of left renal pelvic wall, and percutaneous biopsy was performed. The patient underwent laparoscopic left nephroureterectomy. Seven months later, he was admitted for left flank pain due to a mass along the percutaneous track site. Mass en-bloc resection was performed, and histopathology finding demonstrated undifferentiated carcinoma, compatible with UTUC metastasis. The percutaneous approach should be considered to be the possible cause of tumor seeding. Multimodal therapy seems mandatory, as highlighted in our outcomes, with 5 years of recurrence free survival.

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The role of endoscopic management and adjuvant topical therapy for upper tract urothelial cancer

Chien¹,

Chua²,

Doppalapudi³

et al. 2022

Front. Urol.

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Upper tract urothelial carcinoma (UTUC) has traditionally been managed with radical nephroureterectomy, and while this approach remains the gold standard for high-risk disease, endoscopic, kidney-sparing management has increasingly been adopted for low-risk disease as it preserves kidney function without compromising oncologic outcomes. Ureteroscopy and percutaneous renal access not only provide diagnoses by tumor visualization and biopsy, but also enable treatment with electrocautery or laser ablation. Several modalities exist for laser ablative treatments including thulium:YAG, neodymium:YAG, holmium:YAG, and combinations of the preceding. Furthermore, due to high recurrence rates after endoscopic management, adjuvant intracavitary instillation of various agents such as mitomycin C and bacillus Calmette-Guerin have been used given benefits seen in non-muscle invasive urothelial bladder cancer. Other formulations also being studied include gemcitabine, anthracyclines, and immunotherapies. More recently, Jelmyto, a mitomycin reverse thermal gel, has been developed to allow for adequate drug delivery time and potency since urine flow could otherwise dilute and washout topical therapy. In this article, the authors review techniques, indications, best practices, and areas of current investigation in endoscopic management and adjuvant topical therapy for UTUC.

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Squamous cell carcinoma of the renal pelvis: nephrostomy tract tumour seeding

Cited by 3 publications

References 2 publications

Percutaneous Image-guided Core Needle Biopsy for Upper Tract Urothelial Carcinoma

Percutaneous Image-guided Core Needle Biopsy for Upper Tract Urothelial Carcinoma

Upper Urinary Tract Urothelial Carcinoma Tumor Seeding along Percutaneous Nephrostomy Track: Case Report and Review of the Literature

The role of endoscopic management and adjuvant topical therapy for upper tract urothelial cancer

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