Sporotrichosis With Asteroid Tissue Forms

Importance of the direct fresh examination in the diagnosis of cutaneous sporotrichosis

“…Differing from statements of other authors, 14,19,20 we did not find any relationship between the presence of asteroid bodies and the clinical forms or time of evolution. Moreover, asteroid forms were not only found in old but also in very young lesions (a few days after the beginning of the disease).…”

“…Some authors have called attention to the rarity of asteroid forms in patients from the southern hemisphere 19 . In this regard, it would be interesting to make comparative studies in countries from different regions using the so‐simple methodology proposed here.…”

The Role of Histopathological Examination in the Diagnosis of Cutaneous Sporotrichosis Caused by Sporothrix globosa: A Retrospective Analysis and Reassessment

“…Studies from regions where S. brasiliensi is endemic, such as South America and Latin America, reported a significantly higher chance of asteroid body visualisation. However, the chance of asteroid body visualisation is extremely rare in the Northern Hemisphere [36]. The formation of asteroid bodies may be linked to the virulence of Sporothrix spp., and highly virulent pathogens are more likely to trigger the host immune response and formation of antigen–antibody complexes [37].…”

Retrospective analysis of 71 patients with cutaneous sporotrichosis

“…35 Some researchers emphasised that AB detection was sufficient to provide evidence to initiate sporotrichosis treatment. 36 However, AB is more common in sporotrichosis in South America and South Africa and is rare in the Northern Hemisphere, 37 thus indicating that AB is mainly found in sporotrichosis caused by S. brasiliensis and less frequently in cases of sporotrichosis caused by S. globosa. In our present study, we found that the positive rate of detection for direct microscopy was 40.91%.…”