Spontaneous Pneumothorax

Alfageme, Inmaculada; Moreno, L.; Huertas, Carmen; Vargas, Antonio; Hernández, J. Rodríguez; Beiztegui, Alberto

doi:10.1378/chest.106.2.347

Cited by 78 publications

(13 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some of the techniques for treating persistent pleuropulmonary fistula are well established in thoracic surgery. These techniques include surgical closing of the fistula, open pleural drainage, thoracoplasty, myoplasty and pleurodesis using various sclerosant substances such as talc, tetracycline or bleomycin [15,16]. …”

Section: Discussionmentioning

confidence: 99%

Persistent Pleuropulmonary Air Leak Treated with Autologous Blood: Results from a University Hospital and Review of Literature

Oliveira

Catâneo²,

R³

et al. 2009

Respiration

View full text Add to dashboard Cite

Background: Persistent air leak after pulmonary resection is a difficult complication for thoracic surgeons to manage. Objectives: To show the results of our experience treating persistent pleuropulmonary air leak with autologous blood and review the literature on this specific method of treatment. Methods: Retrospective study of patients with persistent aerial pleuropulmonary fistula treated with autologous blood. The patient’s own blood was collected from a peripheral vein and directly introduced through the pleural drain. An inverted siphon was located in the drainage system to avoid prolonged clamping of the drain. This siphon impeded blood return but not air escape. Results: Between January 2001 and August 2008, 27 patients were treated by the above method. Patient age ranged from 2 to 74 years, and 78% were male. Each procedure used a mean quantity of 92 ml blood. Mean persistent air leak time before pleurodesis was 10.6 days and mean time to fistula resolution after pleurodesis was 1.5 days. Twenty-three (85%) patients had persistent pleuropulmonary air leak closed with the above procedure. Conclusion: Treating persistent pleuropulmonary air leak with autologous blood is promising, but further studies are required to quantify its real effectiveness.

show abstract

Section: Discussionmentioning

confidence: 99%

Persistent Pleuropulmonary Air Leak Treated with Autologous Blood: Results from a University Hospital and Review of Literature

Oliveira

Catâneo²,

R³

et al. 2009

Respiration

View full text Add to dashboard Cite

show abstract

“…[6] Tetrasiklin ile plörodezis uygulanan spontan pnömotoraks olgularında nüks insidansı cerrahi tedavi uygulanan hastalarla karşılaştırıldığında belirgin olarak yüksek bulunmuştur. [17][18][19][20][21] Malign plevral efüzyonların tedavisinde talk, tetrasiklin ve diğer plörodezis ajanları ile karşılaştırıldığında daha efektif sonuçlar elde edildiği çalışmalarla göste-rilmiştir. Uygun ve özellikle cerrahi kimyasal plörode-zis düşünülen spontan pnömotorakslı hastalarda da talk bu amaçla kullanılabilir.…”

Section: Discussionunclassified

Treatment choices in spontaneous pneumothorax

Şengül¹,

Büyükkarabacak²,

Yetim³

et al. 2014

J Kartal TR

View full text Add to dashboard Cite

“…More importantly, studies have reported that its administration does not interfere with subsequent chemotherapy or cause acute respiratory distress syndrome, as talc solution does [31]. However, the production of TCN was discontinued by the manufacturer in 1991 for marketing reasons [31, 32]. As a result alternative agents have been commonly used for chemical pleurodesis [21], although they have not been considered to be as safe as tetracycline [19].…”

Section: Discussionmentioning

confidence: 99%

“…In that study, Varela et al [34]applied OT in patients with pleural effusions and demonstrated that it led to successful pleurodesis in 85.7% of their cases, which is higher than our findings for OT (79.7%). Furthermore, although the dose of TCN may vary between 20 and 30 mg/kg [21, 22, 24, 32, 35], to our knowledge there are no clear data about the dose of OT for its use in pleurodesis. We, however, administered OT at dose of 35 mg/kg in our patients, and although this is higher than the dose of TCN reported, our findings demonstrated that it was adequate for pleurodesis.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Effectiveness of Some Pleural Sclerosing Agents Used for Control of Effusions in Malignant Pleural Mesothelioma: A Review of 117 Cases

et al. 2000

View full text Add to dashboard Cite

Background and Objectives: Management of malignant pleural mesothelioma (MPM) has been an important clinical issue regardless of the treatment modality employed. We aimed to investigate the efficacy of oxytetracycline (OT), Corynebacterium parvum (CP), and nitrogen mustard (NM) in the management of pleural effusion associated with MPM. Methods: One hundred and seventeen patients who had stage-2 MPM or over according to the Butchart staging system and unilateral or bilateral pleural effusion took part in the study. The patients received either OT (35 mg/kg), CP (7 mg), or NM (0.4 mg/kg) through a chest tube for pleurodesis. The association between several clinical parameters and patient survival was also investigated. Results: OT was applied to 59, CP to 29 and NM to 29 cases. A statistical analysis of the results obtained by these agents have demonstrated that OT (30 days, 81%; 90 days, 76.2%) and CP (30 days, 86.2%; 90 days, 79.3%) led to a significantly higher rate of successful pleurodesis as compared to NM (30 days, 48.2%; 90 days, 41.3%; p <0.05). Although the procedure was generally well tolerated by the patients, the NM-treated group experienced significantly more nausea-vomiting (46.1%) and hypotension (35.8%) compared to patients who received OT (nausea-vomiting and hypotension 4.3%; p < 0.001) and CP (nausea-vomiting and hypotension 5.1%; p < 0.001). Furthermore, we found that thrombocytosis, chest pain and weight loss were significantly associated with poor prognosis, whereas epithelial type had a positive effect on survival. Conclusion: These results suggest that OT and CP may be used as effective sclerosing agents for pleurodesis in the control of pleural effusions associated with MPM, without major side effects.

show abstract

Spontaneous Pneumothorax

Cited by 78 publications

References 7 publications

Persistent Pleuropulmonary Air Leak Treated with Autologous Blood: Results from a University Hospital and Review of Literature

Persistent Pleuropulmonary Air Leak Treated with Autologous Blood: Results from a University Hospital and Review of Literature

Treatment choices in spontaneous pneumothorax

Comparison of the Effectiveness of Some Pleural Sclerosing Agents Used for Control of Effusions in Malignant Pleural Mesothelioma: A Review of 117 Cases

Contact Info

Product

Resources

About