Spontaneous pneumomediastinum and subcutaneous emphysema in asthma exacerbation: The Macklin effect

Romero, Kleber J.; Trujillo, Máximo H.

doi:10.1016/j.hrtlng.2009.10.001

Cited by 28 publications

(20 citation statements)

References 30 publications

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“…Patients respond well to this treatment. Similarly in many studies, treatment duration has been reported between 2 to 5 days [1,2,3,12]. Mean hospitalization duration in our study was 4.4 ± 2.17 days.…”

Section: Discussionsupporting

confidence: 81%

“…Narcotic drug use has also been reported among predisposing factors. Primary precipitating factors are cough, sneeze, defecation, childbirth and vomiting [1,2,10]. The most common predisposing factors in our study were smoking with a rate of 62% and asthma with a rate of 33%.…”

Section: Discussionmentioning

confidence: 56%

“…As the air pressure in the mediastinum increases, air leak to the cervical region, within soft tissues and to the retroperitoneal space is seen. These three mechanisms make up the basic pathophysiology of spontaneous pneumomediastinum [1,8].…”

Section: Discussionmentioning

confidence: 99%

“…Spontaneous pneumomediastinum is a subgroup of mediastinum, which does not cause any substantial complications or lifethreatening symptoms and occur without an apparent cause and ameliorate on its own [1]. Its incidence is low.…”

Section: Introductionmentioning

confidence: 99%

“…The increase in pressure difference causes the alveoli to rupture and the air in the pulmonary interstitium accumulate by spreading to the hilus and mediastinum [2][3][4]. Asthma exacerbation, infections (pneumonia, small air way infections) and cough are among the most common reasons [1,5]. The most common clinical findings are chest pain, dyspnea and subcutaneous emphysema [6].…”

Section: Introductionmentioning

confidence: 99%

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Analysis of Patients with Spontaneous Pneumomediastinum

Çakmak¹,

Yüksel²,

Kandemir³

2015

Turk Thorac J

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OBJECTIVES: Spontaneous pneumomediastinum is characterized by the presence of air in the mediastinum without any reason. The objective of this study is to report our experience in the diagnosis and treatment of this clinical condition. MATERIAL AND METHODS:21 patients with spontaneous pneumomediastinum who were referred to our clinic between January 2010 and May 2015 were evaluated retrospectively. The presence of radiological pneumomediastinum and the absence a traumatic cause were taken as the basic criterion. RESULTS:The mean age of the patients was 24.78 ± 4.37 years. Thirteen patients were male, eight patients were female. The main complaints of the patients were chest pain, dyspnea, neck pain, sore throat and cough. Thirteen patients were smokers. Seven patients had a prior history of asthma, five patient had chronic bronchitis and one patient had cronic obstructive lung diseases. No precipitating factor was identified in 9 patients. While initial complaints was associated with physical effort in 7 patients, three patients cough and two patients had a history of severe crying. Pneumomediastinum was diagnosed by chest radiography in 8 patients, and with chest CT in 13 patients. All the patients were performed bronchoscopy and radiograph of esophagus. Electrocardiogram was taken for all patients. Arrhythmia was detected in 4 of the patients. Treatment included analgesia, rest and oxygen therapy. Mortalitiy and morbidity were not seen. The mean length of hospital stay was 4.4 ± 2.17 days. CONCLUSION:Spontaneous pneumomediastinum is a benign process. Despite its low incidence, it should be considered in the differential diagnosis of acute chest pain.

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Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 56%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%