Spontaneous Perforation of the Tympanic Membrane in the First 10 Days of Life

Iacovidou, Nicoletta; Falaena, Vasiliki; Alexaki, Augustina; Nika, Angeliki

doi:10.1055/s-0030-1249763

Cited by 5 publications

(6 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a retrospective study, Iacovidou et al 3 investigated 12 cases of spontaneous perforation of the TM in the first 10 days of life. Cultures of the middle ear exudate grew Pseudomonas aeruginosa in 10, Serratia marcescens in 1, and Staphylococcus aureus in 1.…”

Section: Discussionmentioning

confidence: 99%

“…Hall et al 68 investigated developmental changes in word recognition threshold in children with different middle ear status. The aims were to (1) provide word recognition thresholds (WRTs) at 31, 43, and 61 months of age; (2) investigate developmental changes over time; (3) investigate the relationship between OME and WRT; and (4) investigate the relationship between WRT and hearing thresholds. Around 1000 children were tested longitudinally as part of the Avon Longitudinal Study of Parents and Children (ALSPAC) study, using an adaptive measure of word recognition in quiet.…”

Section: Speech and Language Developmentmentioning

confidence: 99%

“…The specific panel objectives include following: (1) to summarize important new contributions to our understanding of the complications and sequelae of OM, published since the Ninth International Symposium on Recent Advances in Otitis Media in 2007; (2) to determine whether the short-and long-term research goals identified at the previous meeting of this panel have been met; (3) to identify deficiencies in our understanding of the complications and sequelae of OM in specific sites related to the TM (including cholesteatoma), middle ear, inner ear, and intratemporal and intracranial sites, as well as the impact of OM on sound transmission in the middle ear (including TM and ossicles) on hearing and speech and language; (4) to define and prioritize research goals that address deficiencies in our knowledge for investigation during the next 4 years; and (5) to identify the short-and long-term goals for the future and methods by which they can be accomplished.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Panel 8: Complications and Sequelae

Jung¹,

Alper

Hellström³

et al. 2013

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Speech and Language Developmentmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Panel 8: Complications and Sequelae

Jung¹,

Alper

Hellström³

et al. 2013

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

show abstract

“…It is unclear why the youngest infants in the study had a higher prevalence of tympanic membrane perforation documented, although a small case series suggests that it may be related to differences in otopathogens causing AOM in neonates. 10 Our study has several limitations, primarily related to its retrospective nature. In addition to the accuracy of clinician examination findings, we were unable to confirm whether undocumented otologic examination findings were truly absent.…”

Section: Discussionmentioning

confidence: 96%

Otologic Examination Findings In Afebrile Young Infants Clinically Diagnosed With Acute Otitis Media

McLaren

Shah

Schmidt

et al. 2022

Pediatric Infectious Disease Journal

View full text Add to dashboard Cite

There are limited data on examination criteria for diagnosing acute otitis media in young infants. In this 33-site retrospective study of afebrile infants ≤90 days, clinicians typically documented tympanic membrane erythema with ≥1 other otologic abnormalities (64.1%) to diagnose acute otitis media. Notable differences in ear examination findings used for diagnosis existed across age subgroups.

show abstract

“…Available research reports pneumatic otoscopy as unreliable and difficult to perform in young infants due to the small compliant ear canals changing shape with insufflation (Marchant et al, 1986;Marchant et al, 1984a). The horizontal orientation of the tympanic membrane makes clear visualisation difficult, and even when visualised clearly, landmarks are difficult to interpret (Aithal et al, 2012;Baldwin, 2006;Iacovidou, Falaena, Alexaki, & Nika, 2010;Syggelou et al, 2011).…”

Section: Otoscopy and Otomicroscopymentioning

confidence: 99%

Diagnosing conductive dysfunction in infants using wideband acoustic immittance: development and validation of predictive models

Myers¹

View full text Add to dashboard Cite

Background. Infants with early onset of otitis media have greater risk of recurrent and chronic infections that can affect language and development. Diagnostic tools able to quickly and accurately identify middle ear pathology early in infancy could help to facilitate timely intervention for these children.Wideband acoustic immittance (WAI) is an emerging technology for assessing middle ear function with significant advantages over established clinical tests such as tympanometry. WAI does not require pressurization of the ear canal, and is a high-resolution test, measuring middle ear function over a wider frequency range than is possible with tympanometry. Preliminary studies in infants have shown promising results, but further research assessing the diagnostic performance of WAI is needed. Also, the large amount of data generated by WAI can make results difficult to interpret. Research into suitable quantitative techniques to analyse results is still in its infancy. Prediction models are an attractive method for analysis of multivariate data as they can provide individualized probabilities that an infant has middle ear dysfunction. A clinically useful prediction model must be able to accurately discriminate between normal ears and those with middle ear dysfunction, and be well calibrated (i.e., give accurate predictions). However, the number of variables generated by WAI can cause issues with overfitting when developing multivariate models. An overfitted model will accurately describe the data it was developed on, but is likely to perform poorly when applied to new samples. Some form of data reduction or penalization is therefore necessary when modelling WAI. Another issue with developing WAI models is that there are substantial maturational effects on WAI through infancy that need to be controlled for. This can be achieved by either developing models for specific age groups (e.g., a model specifically for neonates), or by controlling for the effect of age by including interactions between age and WAI variables in a model, or by only using developmentally stable regions as predictor variables.Objective. The aim of this work was to investigate the diagnostic performance of WAI in infants by developing predictive models. Data reduction strategies such as selecting predictors based on prior research and principal component analysis were used to increase the likelihood that models would generalize to new samples. The effect of age was initially accounted for by developing age-specific models for neonates, 6-month infants, and 12-month infants (Chapters 2, 3 and 4, respectively). Longitudinal developmental effects on WAI through infancy were then investigated in Chapter 5, and this knowledge was used to develop a model controlling for the effect of age through infancy (6 to 18 months) (Chapter 6, Study 1). The neonate model was assessed for generalizability by applying the model to results from a new sample of infants (Chapter 6, Study 2)ii Methods. Tympanometry, distortion product otoacoustic emissions (DPOAEs) and ...

show abstract

Spontaneous Perforation of the Tympanic Membrane in the First 10 Days of Life

Cited by 5 publications

References 9 publications

Panel 8: Complications and Sequelae

Panel 8: Complications and Sequelae

Otologic Examination Findings In Afebrile Young Infants Clinically Diagnosed With Acute Otitis Media

Diagnosing conductive dysfunction in infants using wideband acoustic immittance: development and validation of predictive models

Contact Info

Product

Resources

About