Spontaneous coronary thrombosis following thrombolytic therapy for acute cardiovascular accident and stroke: a case study

Abstract

Cardiac complications following stroke or acute cerebrovascular accidents (CVA) are common; however, many of these complications are asymptomatic and do not cause adverse cardiac effects. Symptomatic events (such as acute myocardial infarction after CVA) rarely occur and are often the result of an underlying cardiac embolic source, such as a left ventricular thrombus. We report a case of spontaneous coronary thrombosis following thrombolytic therapy for acute CVA, and discuss the implication that an underlying systemic pro-thrombotic state may predispose individuals to thrombosis in disparate vascular beds.

Stroke thrombolysis complicated by ST elevation myocardial infarction (STEMI)

“…The described phenomenon has been reported previously in case reports but we believe this is the first case where STEMI onset has been seen almost immediately following thrombolysis 6 7…”

“…STEMI as a complication of thrombolysis is a rare but recognised complication 4 6 7. We feel this is an important entity for all medical officers involved in the treatment of acute stroke to be aware of.…”

Stroke thrombolysis complicated by ST elevation myocardial infarction (STEMI)

“…The described phenomenon has been reported previously in case reports but we believe this is the first case where STEMI onset has been seen almost immediately following thrombolysis 6 7…”

“…STEMI as a complication of thrombolysis is a rare but recognised complication 4 6 7. We feel this is an important entity for all medical officers involved in the treatment of acute stroke to be aware of.…”

Coronary aspiration thrombectomy after using intravenous recombinant tissue plasminogen activator in a patient with acute ischemic stroke: a case report

“…Three patients who had this therapy were reported, and fortunately, they all survived without intracranial hemorrhagic complications. 2,3,10 This finding indicates the importance of antiplatelets/anticoagulants for preserving the patient’s life to keep their stents from re-occlusion. In our patient, we performed an emergency coronary intervention with the strategy of aspiration thrombectomy without a coronary stent.…”

Does intravenous administration of recombinant tissue plasminogen activator for ischemic stroke can cause inferior myocardial infarction?

“…In the cases that presented with Stewa et al . 9 and Wallace et al , 7 also the patients developed an inferior MI following administration of rTPA. It is not clear if there is any direct correlation between rTPA injection and occurrence of inferior MI, or maybe there is an identical etiology for both of ischemic stroke and inferior MI, as we encounter in aortic dissection.…”

Stroke thrombolysis complicated by ST elevation myocardial infarction (STEMI)

“…The described phenomenon has been reported previously in case reports but we believe this is the first case where STEMI onset has been seen almost immediately following thrombolysis 6 7…”

“…STEMI as a complication of thrombolysis is a rare but recognised complication 4 6 7. We feel this is an important entity for all medical officers involved in the treatment of acute stroke to be aware of.…”

Coronary aspiration thrombectomy after using intravenous recombinant tissue plasminogen activator in a patient with acute ischemic stroke: a case report

“…Three patients who had this therapy were reported, and fortunately, they all survived without intracranial hemorrhagic complications. 2,3,10 This finding indicates the importance of antiplatelets/anticoagulants for preserving the patient’s life to keep their stents from re-occlusion. In our patient, we performed an emergency coronary intervention with the strategy of aspiration thrombectomy without a coronary stent.…”

Does intravenous administration of recombinant tissue plasminogen activator for ischemic stroke can cause inferior myocardial infarction?

“…In the cases that presented with Stewa et al . 9 and Wallace et al , 7 also the patients developed an inferior MI following administration of rTPA. It is not clear if there is any direct correlation between rTPA injection and occurrence of inferior MI, or maybe there is an identical etiology for both of ischemic stroke and inferior MI, as we encounter in aortic dissection.…”

Stroke thrombolysis complicated by ST elevation myocardial infarction (STEMI)

“…The described phenomenon has been reported previously in case reports but we believe this is the first case where STEMI onset has been seen almost immediately following thrombolysis 6 7…”

“…STEMI as a complication of thrombolysis is a rare but recognised complication 4 6 7. We feel this is an important entity for all medical officers involved in the treatment of acute stroke to be aware of.…”

Coronary aspiration thrombectomy after using intravenous recombinant tissue plasminogen activator in a patient with acute ischemic stroke: a case report

“…Three patients who had this therapy were reported, and fortunately, they all survived without intracranial hemorrhagic complications. 2,3,10 This finding indicates the importance of antiplatelets/anticoagulants for preserving the patient’s life to keep their stents from re-occlusion. In our patient, we performed an emergency coronary intervention with the strategy of aspiration thrombectomy without a coronary stent.…”

Does intravenous administration of recombinant tissue plasminogen activator for ischemic stroke can cause inferior myocardial infarction?

“…In the cases that presented with Stewa et al . 9 and Wallace et al , 7 also the patients developed an inferior MI following administration of rTPA. It is not clear if there is any direct correlation between rTPA injection and occurrence of inferior MI, or maybe there is an identical etiology for both of ischemic stroke and inferior MI, as we encounter in aortic dissection.…”