volume 93, issue 0, P3-P-358 2020
DOI: 10.1254/jpssuppl.93.0_3-p-358
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Abstract: The TRPA1 channel is Ca 2+ -permeable non-selective cation channel that shows exquisite sensitivity to reactive oxygen species (ROS). While accumulating evidence has indicated that TRPA1 mediates various physiological functions, such as pain sensing, in mice, the function of TRPA1 is not fully understood in human. Here, we identified and characterized novel splice variants of TRPA1 from human brain cDNA library, one of which excludes the 5′ part of exon 2. Our electrophysiological and intercellular Ca 2+ measu…

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