Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne

Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome

“…In line with other reports, 3,5,7,9,15,17 the present study indicates that combination suppression therapy induces significant subjective improvement in hirsutism, menstrual dysfunction, and acne in PCOS. It also leads to a significant decline in the severity of hirsutism assessed clinically, with a 59.9% reduction in mF-G score.…”

Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome

“…In line with other reports, 3,5,7,9,15,17 the present study indicates that combination suppression therapy induces significant subjective improvement in hirsutism, menstrual dysfunction, and acne in PCOS. It also leads to a significant decline in the severity of hirsutism assessed clinically, with a 59.9% reduction in mF-G score.…”

Reduction of Diameter of Hair Shaft among Women with Hirsutism

“…A Cochrane review 2009 ( (Brown et al, 2009) of nine randomized controlled intervention, two trials that compared 6 months treatment of 100mg /d of spironolactone with placebo was associated with a statistically significant subjective improvement in hair growth and a decrease in Ferriman-Gallway scores (F-G), similar finding also had been revealed in other studies conducted by (Karakurt et al, 2008) and a study conducted by Poll Mara (Spritzer et al, 2000) using the same subjective clinical parameter.…”

Pharmacological and surgical treatment of nonreproductive outcomes in polycystic ovary syndrome: An overview of systematic reviews

“…As some interventions for PCOS have been used for decades, we may have excluded significant earlier studies, albeit potentially of lower quality. In our study, we found that only anti‐androgens were affected by this limitation …”

Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome

“…In line with other reports, 3,5,7,9,15,17 the present study indicates that combination suppression therapy induces significant subjective improvement in hirsutism, menstrual dysfunction, and acne in PCOS. It also leads to a significant decline in the severity of hirsutism assessed clinically, with a 59.9% reduction in mF-G score.…”

Reduction of Diameter of Hair Shaft among Women with Hirsutism

“…A Cochrane review 2009 ( (Brown et al, 2009) of nine randomized controlled intervention, two trials that compared 6 months treatment of 100mg /d of spironolactone with placebo was associated with a statistically significant subjective improvement in hair growth and a decrease in Ferriman-Gallway scores (F-G), similar finding also had been revealed in other studies conducted by (Karakurt et al, 2008) and a study conducted by Poll Mara (Spritzer et al, 2000) using the same subjective clinical parameter.…”

Pharmacological and surgical treatment of nonreproductive outcomes in polycystic ovary syndrome: An overview of systematic reviews

“…As some interventions for PCOS have been used for decades, we may have excluded significant earlier studies, albeit potentially of lower quality. In our study, we found that only anti‐androgens were affected by this limitation …”

Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome

“…In line with other reports, 3,5,7,9,15,17 the present study indicates that combination suppression therapy induces significant subjective improvement in hirsutism, menstrual dysfunction, and acne in PCOS. It also leads to a significant decline in the severity of hirsutism assessed clinically, with a 59.9% reduction in mF-G score.…”

Reduction of Diameter of Hair Shaft among Women with Hirsutism

“…A Cochrane review 2009 ( (Brown et al, 2009) of nine randomized controlled intervention, two trials that compared 6 months treatment of 100mg /d of spironolactone with placebo was associated with a statistically significant subjective improvement in hair growth and a decrease in Ferriman-Gallway scores (F-G), similar finding also had been revealed in other studies conducted by (Karakurt et al, 2008) and a study conducted by Poll Mara (Spritzer et al, 2000) using the same subjective clinical parameter.…”

Pharmacological and surgical treatment of nonreproductive outcomes in polycystic ovary syndrome: An overview of systematic reviews

“…As some interventions for PCOS have been used for decades, we may have excluded significant earlier studies, albeit potentially of lower quality. In our study, we found that only anti‐androgens were affected by this limitation …”