Spinal Cord Compression: An Unusual Manifestation of Pseudohypoparathyroidism

Molecular and Clinical Aspects of Pseudohypoparathyroidism

“…245 Other unusual presenting manifestations of PHP include neonatal hypothyroidism, 151,246 unexplained cardiac failure, 247 Parkinson's disease, 245 and spinal cord compression. 248 The presence of AHO and manifestations of multihormone resistance, such as hypothyroidism or hypogonadism, favors a diagnosis of PHP type 1a/type 1c. 125 By contrast, when hormone resistance is limited to PTH and no features of AHO are present the diagnosis of PHP type 1b is more likely.…”

Molecular and Clinical Aspects of Pseudohypoparathyroidism

“…245 Other unusual presenting manifestations of PHP include neonatal hypothyroidism, 151,246 unexplained cardiac failure, 247 Parkinson's disease, 245 and spinal cord compression. 248 The presence of AHO and manifestations of multihormone resistance, such as hypothyroidism or hypogonadism, favors a diagnosis of PHP type 1a/type 1c. 125 By contrast, when hormone resistance is limited to PTH and no features of AHO are present the diagnosis of PHP type 1b is more likely.…”

Molecular and Clinical Aspects of Pseudohypoparathyroidism

“…245 Other unusual presenting manifestations of PHP include neonatal hypothyroidism, 151,246 unexplained cardiac failure, 247 Parkinson's disease, 245 and spinal cord compression. 248 The presence of AHO and manifestations of multihormone resistance, such as hypothyroidism or hypogonadism, favors a diagnosis of PHP type 1a/type 1c. 125 By contrast, when hormone resistance is limited to PTH and no features of AHO are present the diagnosis of PHP type 1b is more likely.…”

Molecular and Clinical Aspects of Pseudohypoparathyroidism

“…245 Other unusual presenting manifestations of PHP include neonatal hypothyroidism, 151,246 unexplained cardiac failure, 247 Parkinson's disease, 245 and spinal cord compression. 248 The presence of AHO and manifestations of multihormone resistance, such as hypothyroidism or hypogonadism, favors a diagnosis of PHP type 1a/type 1c. 125 By contrast, when hormone resistance is limited to PTH and no features of AHO are present the diagnosis of PHP type 1b is more likely.…”