Abstract:Ion-protein interactions are important for protein function, yet challenging to rationalize due to the multitude of ion-protein interaction possibilities. To explore specific ion effects on protein binding sites, we investigate the interaction of different salts with the zwitterionic peptide triglycine in solution. Dielectric spectroscopy experiments show that salts affect the peptide's reorientational dynamics, with a more pronounced effect of denaturing cations (Li + , guanidinium Gdm + ) and anions (I -, SC… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.