Spectrum of left atrial thrombus in rheumatic heart disease

Mahla, Himanshu; Harlalka, Kaushal K; Bhairappa, Shivakumar; Manjunath, Cholenahally Nanjappa

doi:10.1136/bcr-2014-204370

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…RHD is a condition caused by damage to the heart valves from rheumatic fever (RF), which is an autoimmune response to untreated streptococcal throat infections (240). Left atrial (LA) thrombosis is a common complication with RHD and mitral stenosis (MS) (241). As early as 1991, the luminol-enhanced chemiluminescence technique was used to study the production of oxygen free radicals (OFR) by monocytes and neutrophils in the peripheral blood of patients with RF and RHD (242).…”

Section: Rheumatic Heart Disease (Rhd)mentioning

confidence: 99%

The role of monocytes in thrombotic diseases: a review

Han

Liu

et al. 2023

Front. Cardiovasc. Med.

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Cardiovascular and cerebrovascular diseases are the number one killer threatening people's life and health, among which cardiovascular thrombotic events are the most common. As the cause of particularly serious cardiovascular events, thrombosis can trigger fatal crises such as acute coronary syndrome (myocardial infarction and unstable angina), cerebral infarction and so on. Circulating monocytes are an important part of innate immunity. Their main physiological functions are phagocytosis, removal of injured and senescent cells and their debris, and development into macrophages and dendritic cells. At the same time, they also participate in the pathophysiological processes of pro-coagulation and anticoagulation. According to recent studies, monocytes have been found to play a significant role in thrombosis and thrombotic diseases of the immune system. In this manuscript, we review the relationship between monocyte subsets and cardiovascular thrombotic events and analyze the role of monocytes in arterial thrombosis and their involvement in intravenous thrombolysis. Finally, we summarize the mechanism and therapeutic regimen of monocyte and thrombosis in hypertension, antiphospholipid syndrome, atherosclerosis, rheumatic heart disease, lower extremity deep venous thrombosis, and diabetic nephropathy.

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Section: Rheumatic Heart Disease (Rhd)mentioning

confidence: 99%

The role of monocytes in thrombotic diseases: a review

Han

Liu

et al. 2023

Front. Cardiovasc. Med.

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show abstract

“…Embolism may be the first manifestation of MS, and it can occur even in patients with mild MS before symptom development. 14 In rheumatic mitral valve disease patients, thrombus can occur in areas outside the LA appendage (LAA) 16 and even in the right atrial appendage. 17 …”

Section: Stroke Prevention In Rheumatic Afmentioning

confidence: 99%

Management of atrial fibrillation in rheumatic heart disease

Shenthar

2022

Heart Rhythm O2

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Spectrum of left atrial thrombus in rheumatic heart disease

Cited by 2 publications

References 2 publications

The role of monocytes in thrombotic diseases: a review

The role of monocytes in thrombotic diseases: a review

Management of atrial fibrillation in rheumatic heart disease

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