Spectrophotometric investigation of the binding of vitamin E to water-containing reversed micelles

Calorimetric study of the α-tocopherol solubility in reversed AOT micelles

“…Our next investigations will be addressed to these conditions. Our hypothesis can be confirmed by Avellone et al, data also obtained for AOT reversed micelles with the UV absorption spectroscopy technique [14], as well as by Fukuzawa et al [15], Urano et al [16], and Wassall et al [17] finding that vitamin E molecules are located in the hydrophobic part of the phospholipid bilayer of cell membranes.…”

“…The results of calorimetric investigations on α-tocopherol solubility in AOT reversed micelles were compared to the literature data obtained respectively with UV spectrophotometry [14] for reversed micelles, and for the phospholipid bilayer by other techniques [15][16][17].…”

Stability of Vitamins C and E in Topical Microemulsions for Combined Antioxidant Therapy

“…The molecule of vitamin E has two distinct domains; a chromanol nucleus terminated by a polar OH group and a long hydrophobic phytyl side chain (Figure 9) (Bongiorno et al 2006;Avellone et al 2002). We confirmed that vitamin E is freely soluble in the oily phase as well as in the surfactant mixture of ME, so we assume that, in the ME, it partitions between the oily phase and the surfactant mixture.…”

“…We confirmed that vitamin E is freely soluble in the oily phase as well as in the surfactant mixture of ME, so we assume that, in the ME, it partitions between the oily phase and the surfactant mixture. Avellone et al (2002) showed that the chromanol ring of vitamin E competes with water molecules for binding sites on hydrophilic regions of surfactant. When the content of water is increased, the concentration of vitamin E in the surfactant mixture decreases.…”

Chitosan-coated nanoliposome as vitamin E carrier

“…The phenolic hydroxyl group of vitamin E donates hydrogen atoms, acting as a membrane stabilizing agent and free radical scavenger which can prevent the peroxidation of the polyunsaturated fatty acyl chains of membrane lipids [20][21][22][23] .…”