2019
DOI: 10.15171/ps.2019.30
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Spectrofluorimetric Determination of Atenolol and Carvedilol in Pharmaceutical Preparations after Optimization of Parameters using Response Surface Methodology

Abstract: Background: The present work is aimed to study the effect of different parameters on the fluorescence intensity of atenolol (ATE) and carvedilol (CAR) and optimization by response surface methodology (RSM) to provide a simple analytical method for their quantification in pharmaceutical formulations. Methods: Various parameters affecting the fluorescence intensity, i.e., sodium dodecyl sulfate (SDS) concentration, pH, volume fraction of solvents were optimized using RSM. Then, the optimized parameters were appl… Show more

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Cited by 3 publications
(1 citation statement)
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“…In literature research, UV-Visible spectrophotometry (Saleem, 2019;Antakli et al, 2020;Mohammad et al, 2019;Vaikosen et al, 2020), spectrofluorometry (Tabrizi and Yousefzadeh, 2019), high-performance liquid chromatography (HPLC) (Pires de Abreu et al, 2003;Iha et al,. 2002;Chiu et al, 1997;Madhusudhan et al, 2018;El-Alfy et al, 2019;Elkady et al, 2020), gas chromatography-mass spectrometry (GC-MS) (Yilmaz et al, 2009) and capillary electrophoresis (Arias et al, 2001) methods for determining atenolol in invitro conditions and biological materials have been reached.…”
Section: Introductionmentioning
confidence: 99%
“…In literature research, UV-Visible spectrophotometry (Saleem, 2019;Antakli et al, 2020;Mohammad et al, 2019;Vaikosen et al, 2020), spectrofluorometry (Tabrizi and Yousefzadeh, 2019), high-performance liquid chromatography (HPLC) (Pires de Abreu et al, 2003;Iha et al,. 2002;Chiu et al, 1997;Madhusudhan et al, 2018;El-Alfy et al, 2019;Elkady et al, 2020), gas chromatography-mass spectrometry (GC-MS) (Yilmaz et al, 2009) and capillary electrophoresis (Arias et al, 2001) methods for determining atenolol in invitro conditions and biological materials have been reached.…”
Section: Introductionmentioning
confidence: 99%