volume 66, issue 6, P3883-3887 1992
DOI: 10.1128/jvi.66.6.3883-3887.1992
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J Liu, N D Perkins, R M Schmid, G J Nabel

Abstract: NF-kappa B is a protein complex which functions in concert with the tat-I gene product to stimulate human immunodeficiency virus (HIV) transcription. To determine whether specific members of the NF-kappa B family contribute to this effect, we have examined the abilities of different NF-kappa B subunits to act with Tat-I to stimulate transcription of HIV in Jurkat T-leukemia cells. We have found that the p49(100) DNA binding subunit, together with p65, can act in concert with Tat-I to stimulate the expression o…

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