Specific disgust processing in the left insula: New evidence from direct electrical stimulation

Papagno, Costanza; Pisoni, Alberto; Mattavelli, Giulia; Casarotti, Alessandra; Comi, Alessandro; Fumagalli, Francesca; Vernice, Mirta; Fava, Enrica; Riva, Marco; Bello, Lorenzo

doi:10.1016/j.neuropsychologia.2016.01.036

Cited by 63 publications

(38 citation statements)

References 41 publications

(48 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This can be supported by a recent study in which direct electrical stimulation was applied to the left insula during awake surgery in thirteen patients causing a decreased recognition of all negative emotions [39]. Another study found that impaired emotion recognition was associated with dysfunction of a bilateral fronto-temporal-limbic network in 180 patients with traumatic brain injury (TBI) [40].…”

Section: Discussionmentioning

confidence: 85%

Impaired Emotion Recognition after Left Hemispheric Stroke: A Case Report and Brief Review of the Literature

Aben

Reijmer

Visser-Meily

et al. 2017

Case Reports in Neurological Medicine

View full text Add to dashboard Cite

Impaired recognition of emotion after stroke can have important implications for social competency, social participation, and consequently quality of life. We describe a case of left hemispheric ischemic stroke with impaired recognition of specifically faces expressing fear. Three months later, the patient's spouse reports that the patient was irritable and slow in communication, which may be caused by the impaired emotion recognition. The case is discussed in relation to the literature concerning emotion recognition and its neural correlates. Our case supports the notion that emotion recognition, including fear recognition, is regulated by a network of interconnected brain regions located in both hemispheres. We conclude that impaired emotion recognition is not uncommon after stroke and can be caused by dysfunction of this emotion-network.

show abstract

Section: Discussionmentioning

confidence: 85%

Impaired Emotion Recognition after Left Hemispheric Stroke: A Case Report and Brief Review of the Literature

Aben

Reijmer

Visser-Meily

et al. 2017

Case Reports in Neurological Medicine

View full text Add to dashboard Cite

show abstract

“…Evaluating the alcoholic additionally recruited the anterior insula, the dmPFC and other patches in the ATL and IFC (pars triangularis). Because the anterior insula has been causally linked to the experience of disgust in studies of invasive [158][159][160] and non-invasive 161,162 brain stimulation, and the SCM predicts disgust to be a unique reaction to cold-incompetent out-groups 62 , it would be tempting to suggest that our findings provide support for the latter. Our findings concerning the network of empathic concern towards the elderly characters also seem to support the SCM prediction for the social emotions that respondents might experience 62 .…”

Section: Regionmentioning

confidence: 80%

Group membership dictates the neural correlates of social optimism biases

Dricu

Schüpbach

Bristle

et al. 2020

Sci Rep

View full text Add to dashboard Cite

optimism bias, i.e. expecting the future to hold more desirable than undesirable outcomes, also extends to people that we like or admire. However, it remains unknown how the brain generates this social optimism bias. in this study, respondents estimated the likelihood of future desirable and undesirable outcomes for an in-group and three out-groups: warm-incompetent, cold-competent, and cold-incompetent. We found a strong social optimism bias for the in-group and the warm outgroup and an inverted pattern for the cold-incompetent out-group. for all groups, scores of social optimism bias correlated with the brain activity in structures that respondents differentially engaged depending on the target social group. in line with our hypotheses, evaluating the in-group recruited the ventromedial prefrontal cortex and the precuneus/posterior cingulate cortex, whereas evaluating the warm out-group engaged the posterior insula, mid cingulate cortex, and somatosensory cortices. these findings suggest different underlying cognitive mechanisms of social optimism bias for these groups, despite similar behavioural patterns. thinking about the cold out-groups recruited the right anterior temporal lobe, and temporoparietal junction. evaluating the cold-incompetent out-group additionally recruited the anterior insula, inferior frontal cortex and dorsomedial frontal cortex. We discuss these neuroimaging findings with respect to their putative cognitive functions. Human minds are highly capable of solving problems at hand, anticipating prospective issues and benefits, and planning accordingly. At the core of these skills lies the capacity to gauge the likelihood of future events 1-3. The way we assess the likelihood of future events in the general population is different from how we assess it for ourselves 4-6 , for those close to us 7-10 , and for in-group 11,12 and out-group members 11-19. Through various motivational 20,21 and cognitive mechanisms 22,23 , we manifest an optimism bias whenever we think about our future and the future of those close to us 4,8,10,11,13 but not of acquaintances or dissimilar others 8,11,14,24,25. Specifically, we expect that the future holds significantly more desirable than undesirable outcomes for ourselves and those we identify with 26. Despite a modest body of behavioural research on social optimism bias, i.e. optimism manifested towards people that we like and feel close to, very little is known about how the brain gives rise to this phenomenon 18. The primary focus of the current study was to investigate the neural correlates of group membership-driven optimism biases. To pursue this research aim and inform our hypotheses, we considered the neuroimaging literature on person perception and social cognition. A hallmark of social cognition is that individuals think differently about in-group and out-group members 27-32. Although what determines in-group and out-group membership is flexible and highly contextual 30,33 , people perceive in-group and out-group members as part of different entities wi...

show abstract

“…painful physical or thermal heat stimuli) and to expressions of disgust, fear, anxiety, and happiness. In a meta-analysis of fMRI studies on empathy, Fan et al 68 found that the right anterior insula was associated with the affective-perceptual form of empathy, while the left insula was associated with both the affective-perceptual and cognitive-evaluative forms of empathy. The role of the insula in empathy and social cognition has been confirmed in lesion studies.…”

Section: Insula Functionmentioning

confidence: 99%

Structure and Function of the Human Insula

Uddin

Nomi

Hébert-Seropian

et al. 2017

Journal of Clinical Neurophysiology

873

604

View full text Add to dashboard Cite

The insular cortex, or “Island of Reil”, is hidden deep within the lateral sulcus of the brain. Subdivisions within the insula have been identified on the basis of cytoarchitectonics, sulcal landmarks, and connectivity. Depending on the parcellation technique employed, the insula can be divided into anywhere between 2 and 13 distinct subdivisions. The insula subserves a wide variety of functions in humans ranging from sensory and affective processing to high-level cognition. Here we provide a concise summary of known structural and functional features of the human insular cortex with a focus on lesion case studies and recent neuroimaging evidence for considerable functional heterogeneity of this brain region.

show abstract

Specific disgust processing in the left insula: New evidence from direct electrical stimulation

Cited by 63 publications

References 41 publications

Impaired Emotion Recognition after Left Hemispheric Stroke: A Case Report and Brief Review of the Literature

Impaired Emotion Recognition after Left Hemispheric Stroke: A Case Report and Brief Review of the Literature

Group membership dictates the neural correlates of social optimism biases

Structure and Function of the Human Insula

Contact Info

Product

Resources

About