Nylidrin, a β‐adrenoreceptor stimulant drug, blocks the spasmogenic action of acetylcholine, histamine and barium on guinea‐pig ileum in vitro and bronchial muscles in vivo. This action is antagonized by the β‐receptor blocking agent, propranolol. It is suggested that the antispasmodic effect of nylidrin is mediated through the activation of β‐receptors. Nylidrin seems to be less potent but longer acting in its antispasmodic action than isoprenaline.
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